Scleritis (inflammation of the sclera): symptoms, causes, diagnosis and treatment

This condition rarely resembles a common irritation. The eye becomes red, the pain becomes very severe, sometimes radiating to the temple or intensifying with movement. This type of inflammation of the sclera affects more than just the superficial mucous membrane. The tough outer layer of the visual apparatus is also affected.

Therefore, an in-person examination is necessary for scleritis. This condition should never be treated at home with eye drops for irritation.

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What is scleritis and why is it dangerous?

What is scleritis and why is it dangerous?

The sclera is a dense, white membrane. It maintains the shape of the eyeball and protects its internal structures. With scleritis, inflammation affects the deep layers of this membrane. Due to its rich innervation, pain can be severe. It interferes with sleep, reading, and looking at light.

Scleritis can be anterior or posterior. The anterior type is often noticeable by deep redness, while the posterior type can masquerade as other conditions and manifest as:

  1. Pain
  2. Vision loss
  3. Tissue swelling

This is why diagnosing scleritis involves more than just a physical examination.

Why this condition shouldn't be ignored

Inflammation of the membrane is associated with autoimmune diseases, infections, injuries, or complications after surgery. Without treatment, there is a risk of corneal, choroidal, and retinal involvement, as well as increased intraocular pressure. Complications depend on the type and severity of the condition.

Causes and risk factors of scleritis

In some patients, the disease is associated with systemic inflammation. It is detected:

  • Rheumatoid arthritis
  • Vasculitis
  • Inflammatory bowel disease
  • Other autoimmune diseases

In such situations, an ophthalmologist works in conjunction with a rheumatologist or general practitioner.

Infections, injuries, and surgeries

Infectious scleritis is less common. However, it requires special care. Inflammation can occur after injury, surgery, or the spread of infection from adjacent tissues. Treatment of scleritis in this case depends on the pathogen and the depth of the lesion.

When inflammation of the sclera is associated with general diseases of the body

If symptoms of the disease recur or are severe, the doctor looks for an underlying cause. Tests, consultations with related specialists, and evaluation of systemic symptoms help understand the cause of the disease. This investigation is important for preventing relapses.

Causes and risk factors of scleritis

Symptoms of scleritis

The main symptom is a deep, aching, or piercing pain in the eye, sometimes worsening at night. The redness of the eye is not superficial, but darker, purple-red. The discomfort may increase with touching or moving the eye.

Symptoms of scleritis
  • Photophobia, lacrimation and a feeling of pressure These symptoms arise from irritation of the inflamed tissues and adjacent structures. The patient may feel pressure, distension, or pain around the eye. These complaints cannot be explained solely by fatigue or dryness.
  • Decreased vision and other warning signs These signs indicate a risk of deep involvement or complications. If the image becomes cloudy, pain occurs when moving the eye, photophobia, or severe redness occurs, consult a doctor immediately.
  • Anterior and posterior variants of the disease: what are the differences? Anterior scleritis is more often visible upon examination: the eye becomes red and painful. Posterior scleritis manifests as pain, blurred vision, limited eye movement, and swelling around the optic nerve. To determine the exact type, the doctor prescribes diagnostic imaging tests.

How to distinguish scleritis from other eye diseases

This condition is often confused with conjunctivitis, uveitis, and keratitis. However, the urgency and treatment strategies for these conditions differ. A comparison helps highlight the key differences.

SignatureScleritisConjunctivitisUveitis
PainSevere, deepUsually mildSevere
RednessDeepSuperficialMay be severe
PhotophobiaOften presentRarelyOften Yes
Risk of vision lossYesUsually lowerYes

Even with similar symptoms, the final conclusion is made by an ophthalmologist. Pain and photophobia should be treated with particular caution: these symptoms rarely occur with simple irritation.

Scleritis and conjunctivitis

With conjunctivitis, the mucous membrane becomes inflamed, and there is often discharge and a gritty sensation. With scleritis, the pain is deeper, the redness is denser, and vasoconstrictor drops do not solve the problem. Treating scleritis as conjunctivitis can delay proper care.

Scleritis and uveitis

Uveitis affects the choroid and often causes photophobia, pain, and blurred vision. Scleritis can coexist with uveitis, so the doctor evaluates the anterior segment of the eye, pressure, the cornea, and the depth of inflammation.

Scleritis and keratitis

Keratitis is an inflammation of the cornea. It often causes burning, photophobia, a foreign body sensation, and decreased vision. If the cornea is involved in scleritis, the risk of complications is higher, and treatment requires special monitoring.

Diagnosing scleritis: how an ophthalmologist examines

Diagnosis of scleritis begins with a detailed examination of the patient's complaints. The doctor will ask:

  • When the pain began
  • Was there a fever, trauma, surgery, or systemic disease?

Then a biomicroscopy is performed—an examination of the eye under magnification. The doctor assesses the depth of redness, the condition of the cornea, anterior chamber, and blood vessels.

Instrumental diagnostic methods

If posterior scleritis is suspected, ultrasound, OCT, fundus examination, and other tests may be necessary. These can help detect swelling, changes in the membranes, and possible complications. The extent of the examination depends on the clinical presentation.

Analysis and consultations with related specialists

If the doctor suspects a systemic cause, blood tests and consultations with specialized specialists are ordered. This helps select not only local anti-inflammatory therapy but also systemic medications as indicated.

General information

Treatment: how we select therapy

Therapy may not be the same for everyone. Autoimmune inflammation, infection, and postoperative complications require different solutions. The doctor evaluates:

  1. The form and depth of the process
  2. Risk of complications
  3. The patient's general condition

Drug therapy

Treatment may include anti-inflammatory drugs, systemic medications, infection therapy, and supportive measures. Do not self-administer steroid, antibacterial, or vasoconstrictor drops. Incorrect treatment can worsen the disease.

Dynamic monitoring and complication management

After starting therapy, the doctor monitors pain, redness, vision, and the condition of the cornea and deep structures. Dynamic monitoring allows for the early detection of complications or relapses. If the cause is systemic, general disease monitoring is important.

"In our practice, scleritis is often initially mistaken for ordinary eye redness. Therefore, we emphasize a detailed diagnosis: this helps us quickly differentiate scleritis from conjunctivitis, uveitis, and other inflammatory diseases, and save time." — ophthalmologist

Treatment: how we select therapy

Why it's important not to self-medicate

Drops that temporarily reduce redness do not treat scleral inflammation. They can create a false sense of improvement while the inflammation remains active. Self-medication is especially risky in cases of severe pain and photophobia.

Why you shouldn't delay a visit to the doctor

Inflammation of the scleral membrane can progress and involve adjacent tissues. The sooner you see an ophthalmologist, the faster the disease can be diagnosed and the risk of complications can be reduced. If you wear contact lenses, they should be removed before the examination.

Why it's important not to self-medicate

Why patients choose our approach

At K+31, we focus on differential diagnosis. The doctor distinguishes this disease from similar conditions and evaluates for a systemic cause.

Individualized treatment plan

The treatment plan is developed only after an examination and testing. The patient receives clear explanations:

  1. What is inflamed?
  2. Why is this important?
  3. What monitoring steps are needed?

Monitoring until the condition stabilizes

We monitor the patient until the inflammation subsides and the condition stabilizes. If necessary, related specialists are involved.

Why patients choose our approach

Prevention and management of relapses

It is important to monitor autoimmune diseases, treat infections, protect the eyes from injury, and return for follow-up care after inflammation. If a relapse occurs, seek medical attention before symptoms become severe.

When is a follow-up examination necessary?

A follow-up examination is necessary if pain increases, redness returns, photophobia appears, or vision deteriorates. These signs may indicate recurrence of the condition.

Symptoms that require an immediate visit to an ophthalmologist:

  • Severe pain
  • Deep redness
  • Photophobia
  • Decreased vision
  • Pain with visual movement

If the pain intensifies, photophobia develops, or vision deteriorates, time is of the essence with scleritis.

Prevention and management of relapses

Patient's pathway for suspected scleritis

If severe pain and deep redness are present, we try not to delay the initial examination. The doctor first rules out conditions that require urgent action, such as keratitis, uveitis, acute increase in intraocular pressure, and trauma. After this, the doctor determines the type of scleral inflammation and determines what further tests are needed.

If the diagnosis is confirmed, the patient receives not only a prescription but also an explanation of the pathology: when to return for a follow-up appointment, what tests to take, and which specialist to consult if a systemic cause is suspected. This is important because relapse is often associated not with "unsuccessful eye drops," but with the activity of the underlying disease.

What does the doctor evaluate during a follow-up examination?

At the follow-up appointment, the ophthalmologist checks to see if the pain is subsiding, if the intensity of redness is changing, if photophobia persists, and if vision has decreased. Instrumental examinations are repeated if necessary. Monitoring is necessary until the condition stabilizes, not just until initial relief.

Why an interdisciplinary approach is important?

If the inflammation is associated with autoimmune diseases, treating the eye alone is not enough. The ophthalmologist may recommend a consultation with a rheumatologist, internist, or infectious disease specialist. This interdisciplinary approach reduces the risk of recurrent episodes and helps to more safely select systemic medications.

Patient's pathway for suspected scleritis
What questions should you ask your doctor?

During the appointment, it's helpful to clarify the diagnosed form of the disease, whether there are signs of corneal involvement or uveitis, and whether tests and consultations with related specialists are needed. It's important for the patient to understand which symptoms should improve first and when treatment should be reconsidered.

We specifically explain that treatment should not be discontinued just because the pain has subsided. Inflammatory activity is assessed by examination, not just by sensation. This monitoring helps to more safely stabilize treatment.

FAQ

What is scleritis and why is it dangerous?

Scleritis is an inflammation of the sclera, the tough outer layer of the eye. It can cause severe pain, risk of complications, and decreased vision, especially if the inflammation affects deeper structures.

How can you differentiate scleritis from conjunctivitis?

With scleritis, the pain is usually more severe, the redness is deeper, and there is often photophobia and discomfort when moving the eye. With conjunctivitis, there is more often superficial redness and discharge.

Can scleritis be treated at home?

No. Scleritis requires an in-person examination by an ophthalmologist, as treatment depends on the cause of the inflammation. It's impossible to choose the right treatment on your own.

When should you see a doctor immediately?

If you experience severe pain, photophobia, blurred vision, severe redness, or pain when moving your eye, you should see an ophthalmologist as soon as possible.
Conclusions

Conclusions

Scleritis is a condition in which superficial redness can mask underlying inflammation. Schedule a consultation at K+31 if your eye is sore, red, or has difficulty tolerating light. An ophthalmologist will diagnose scleritis, determine the cause, and prescribe treatment without any dangerous guesswork.

List of sources

Clinical Guidelines Portal of the Russian Ministry of Health — https://cr.minzdrav.gov.ru/

Russian Medical Journal — https://www.rmj.ru/

Media Sfera Publishing House — https://www.mediasphera.ru/

CyberLeninka (search for "scleritis") — https://cyberleninka.ru/

eLIBRARY.RU - https://elibrary.ru/

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