Penile cancer

This is a rare tumor, and due to the sensitivity of the topic, men often seek treatment late. Penile cancer, or penile cancer, develops slowly and is highly treatable in its early stages, often with organ preservation. The first changes are visible to the naked eye, but they can easily be mistaken for an infection.

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What is penile cancer?

What is penile cancer?

This is a malignant tumor of the penis, originating from skin and mucosal cells. It is most often a squamous cell carcinoma. Penile tumors (penile cancer) are rare, but their incidence increases with age, and early detection determines the outcome. This problem is addressed by penile oncology.

Symptoms of penile cancer

Symptoms of penile cancer

The disease rarely occurs secretly. Symptoms of penile cancer are usually noticeable to the man himself, but they are often mistaken for an infection.

Early signs of the disease

At the start, local changes appear: a non-healing ulcer, erosion, compaction or spot on the head or foreskin.

Symptoms in later stages

Later the picture is brighter: tumor growth, bleeding, discharge with an unpleasant odor; the inguinal lymph nodes are enlarged.

When you need to see a doctor “K+31”

Any persistent change in the skin of an organ is a reason for examination. You should make an appointment with an oncologist if you have:

  • Non-healing ulcer on the penis
  • Seal or assembly
  • Skin color change
  • Discharge with an unpleasant odor
  • Bleeding
  • Enlarged inguinal lymph nodes

It is especially important not to wait if the wound does not heal for more than two to three weeks.

Causes and risk factors

It's difficult to pinpoint the exact cause, but key factors are known and help ensure timely examination.

Human papillomavirus (HPV)

Infection plays a major role. HPV is detected in a significant proportion of cases, so the link between HPV and penile cancer is considered proven.

Chronic inflammatory processes

Long-term irritation also plays a role: chronic balanitis, phimosis, and poor hygiene promote inflammation, which increases the risk.

Other risk factors

Additionally, smoking, age, untreated phimosis, and decreased immunity are significant factors.

Stages of penile cancer

Stages of penile cancer

The stage is determined by the depth of tumor invasion in the penis and lymph node involvement. Penile cancer stages are divided into three groups; these determine the extent of treatment and prognosis.

Localized tumor

The tumor is limited to superficial tissues. This is the most favorable option, often allowing organ preservation.

Regional spread

Tumor cells have reached the inguinal lymph nodes. In this case, their removal and additional therapy are added to treatment.

Disseminated tumor process

The tumor has grown deeper or has caused distant metastases, which require systemic drug treatment.

Diagnosis of penile cancer

An examination confirms the diagnosis and determines the stage. Diagnosis of penile cancer is based on examination, biopsy, and imaging and usually follows these steps:

  1. Examination and consultation with a specialist
  2. Biopsy of the affected area
  3. Ultrasound of the groin and radiation methods
  4. Determining the stage of the disease

Without tissue examination, the diagnosis is not considered confirmed.

Specialist examination and consultation

They begin with an examination. This includes an assessment of the tumor, inguinal lymph nodes, and the patient's general condition.

Biopsy and morphological examination

The diagnosis is confirmed by tissue analysis. A penile biopsy with histological examination accurately determines the tumor type.

Instrumental diagnostics

To assess the spread of the tumor, ultrasound is used, and if necessary, CT or MRI; these methods show the condition of the lymph nodes and the depth of invasion.

Determining the stage of the disease

The examination results in the precise stage of the disease, which determines the choice of surgery.

Our specialists especially value early consultation.

"In our practice, early diagnosis of penile cancer is crucial. In the early stages, organ-preserving treatments are often successful, maintaining the patient's quality of life. To determine the optimal approach, we consider each case individually and involve specialists from various fields."

Modern treatment methods

The treatment plan depends on the stage and is always individualized. Penile cancer treatment combines several methods, which are conveniently compared in the table:
Method When used Advantages Limitations
Organ-preserving treatment Early superficial tumors Preservation of anatomy and function Not suitable for deep invasion
Surgical treatment Localized and locally advanced forms Radical tumor removal Functional and cosmetic consequences
Radiation therapy Early stages, refusal of surgery Organ preservation Radiation reactions, risk of recurrence
Drug therapy Advanced disease, metastases Systemic effects Side effects, requires monitoring
Methods are often combined. Below are more details about each.

Surgical treatment

Surgery remains the primary treatment option. Surgical treatment involves removing the penile tumor within the healthy tissue.

Organ-preserving surgeries

Whenever possible, the organ is preserved: organ-preserving surgeries remove only the tumor and are suitable for early stages.

Radiation therapy

Radiation therapy is an alternative to surgery in the early stages. Radiation therapy allows for organ preservation, but requires monitoring due to the risk of recurrence.

Drug-based antitumor therapy

For advanced disease, medications are used. Antitumor therapy—chemotherapy, sometimes immunotherapy—affects the tumor systemically.

General information

How is treatment performed?

Penile cancer treatment is structured so that decisions are made thoughtfully and in consultation with your doctor.

Initial consultation

It all starts with an appointment. The oncologist's consultation includes an examination, biopsy review, and a discussion of options.

Developing a personalized plan

The treatment plan is determined by a consultation. The plan takes into account the stage, tumor type, age, and the patient's desire to preserve the organ.

Results monitoring

During treatment, the doctor evaluates the tumor's response and adjusts the plan if necessary.

How is treatment performed?

Post-treatment rehabilitation and monitoring

After completing treatment for penile cancer, the patient remains under observation for several years, which typically includes:

  • Regular examinations with an oncologist
  • Monitoring the condition of the inguinal lymph nodes
  • Ultrasound and, if necessary, CT scan
  • Assessment of healing and organ function
  • Psychological support, if needed

This monitoring helps maintain remission and detect relapses early.

Post-treatment rehabilitation and monitoring

Benefits of contacting us

Penile cancer requires the coordinated work of an oncologist and a urologist-oncologist, and our center provides this approach. What the patient receives:

  • Specialization in oncological diseases
  • A team of oncologists, urologists, and related specialists
  • Modern diagnostics and a personalized plan
  • Organ-preserving approaches when indicated
  • Consultation in complex cases
  • Support and outcome monitoring at all stages

This format increases the chances of organ preservation and quality of life.

Benefits of contacting us

Answers to frequently asked questions

Below are frequently asked questions from patients.

What symptoms may indicate penile cancer?

The main signs of penile cancer are a non-healing ulcer, a lump, skin discoloration, discharge, or bleeding. Any such sign requires examination.

Can penile cancer be cured?

With early treatment, yes, often with organ preservation. The treatment strategy depends on the stage and type of tumor.

What diagnostic methods are used?

Examination, biopsy with histology, ultrasound, if necessary CT or MRI to assess the extent.

Is surgery always necessary?

No. In the early stages, organ-preserving methods and radiation therapy are possible; the doctor makes the choice after an examination.
Conclusion

Penile cancer is curable, especially when caught early; modern cancer treatments often allow the organ to be preserved. Don't put off a visit out of embarrassment; delaying it reduces your chances. If you notice any signs of penile cancer, schedule a consultation with an oncologist.

List of sources

Clinical Guidelines of the Ministry of Health of the Russian Federation. Penile Cancer — https://cr.minzdrav.gov.ru/

Category of Clinical Guidelines of the Ministry of Health of the Russian Federation — https://cr.minzdrav.gov.ru/

Russian Society of Clinical Oncology (RUSSCO) — https://rosoncoweb.ru

Russian Society of Urologists — ttps://uroweb.ru

eLIBRARY Scientific Electronic Library — https://elibrary.ru

CyberLeninka — https://cyberleninka.ru

MSD Manual (Russian version) — https://www.msdmanuals.com/ru

National Medical Research Center of Oncology of the Ministry of Health of Russia — https://www.oncology.ru

National Medical Research Center of Radiology of the Russian Ministry of Health — https://nmicr.ru

N.N. Blokhin National Medical Research Center of Oncology of the Russian Ministry of Health — https://www.ronc.ru

Our doctors

Merkulov Igor Alexandrovich
Experience 34 years
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Merkulov
Igor Alexandrovich
Deputy Chief Physician for Oncology, Oncologist
Ershova Ksenia Igorevna
Experience 23 years
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Ershova
Ksenia Igorevna
Head of department, oncologist
Abashin Sergey Yuryevich
Experience 43 years
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Abashin
Sergey Yuryevich
Head of oncology projects, oncologist
Balkarov Beslan Khasenovich
Experience 17 years
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Balkarov
Beslan Khasenovich
Surgeon, oncologist, acting head of the surgical department
Volkova Daria Mikhailovna
Experience 17 years
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Volkova
Daria Mikhailovna
Head of the Department of Radiation Therapy, Radiotherapist
Morozova Albina Soslanovna
Experience 18 years
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Morozova
Albina Soslanovna
Acting head of the department of antitumor drug therapy, oncologist
Chudnykh Sergey Mikhaylovich
Experience 42 years
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Chudnykh
Sergey Mikhaylovich
Rukovoditel Tsentra Endokrinologii I Korrektsii Metabolicheskikh Narusheniy
Glotov Egor Maksimovich
Experience 11 years
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Glotov
Egor Maksimovich
Thoracic surgeon
Khromov Roman Aleksandrovich
Experience 22 years
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Khromov
Roman Aleksandrovich
Urologist
Berestok Tatyana Sergeevna
Experience 11 years
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Berestok
Tatyana Sergeevna
Oncologist, Mammologist, Plastic Surgeon
Pereverzev Maksim Andreevich
Experience 11 years
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Pereverzev
Maksim Andreevich
Oncologist-Mammologist, Plastic Surgeon
Kalakutskaya Natalia Lvovna
Experience 28 years
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Kalakutskaya
Natalia Lvovna
Doctor-oncologist
Malygin Sergey Evgenyevich
Experience 31 year
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Malygin
Sergey Evgenyevich
Oncologist-mammologist, surgeon
Pshikhachev Ahmed Mukhamedovich
Experience 23 years
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Pshikhachev
Ahmed Mukhamedovich
Urologist, Oncologist
Shevchuk Alexei Sergeyevich
Experience 26 years
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Shevchuk
Alexei Sergeyevich
Oncogynecology consultant, obstetrician-gynecologist
Chichkanova Tatyana Vladimirovna
Experience 25 years
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Chichkanova
Tatyana Vladimirovna
Oncologist-mammologist, radiologist
Ovsiy Oksana Gennadievna
Experience 14 years
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Ovsiy
Oksana Gennadievna
Doctor-oncologist
Katz Ksenia Vladimirovna
Experience 12 years
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Katz
Ksenia Vladimirovna
Dermatologist, oncologist, cosmetologist
Korshikova Kamila Mukhtorovna
Experience 5 years
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Korshikova
Kamila Mukhtorovna
Radiotherapist
Ter-Arutyunyants Svetlana Andreevna
Experience 27 years
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Ter-Arutyunyants
Svetlana Andreevna
Radiotherapist, oncologist
Udin Oleg Ivanovich
Experience 32 years
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Udin
Oleg Ivanovich
Deputy chief physician for surgery, surgeon
Kogonia Lali Mikhailovna
Experience 52 years
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Kogonia
Lali Mikhailovna
Chemotherapist
Gomov
Mikhail Alexandrovich
Consultant in oncogynecology, obstetrician-gynecologist
Menkes (Ryabova) Yulia Alexandrovna
Experience 5 years
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Menkes (Ryabova)
Yulia Alexandrovna
Oncologist-chemotherapist
Grishin Igor Igorevich
Experience 33 years
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Grishin
Igor Igorevich
Obstetrician-gynecologist
Achba Maya Otarovna
Experience 18 years
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Achba
Maya Otarovna
Radiologist, ultrasound diagnostician, oncologist-mammologist
Lukyanenko Vladimir Alexandrovich
Experience 18 years
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Lukyanenko
Vladimir Alexandrovich
Oncologist-mammologist
Volenko Ivan Alexandrovich
Experience 15 years
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Volenko
Ivan Alexandrovich
Surgeon-oncologist-mammologist, plastic surgeon
Yakovleva Yana Sergeevna
Experience 8 years
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Yakovleva
Yana Sergeevna
Radiotherapist
Ivanova Olga Vladimirovna
Experience 26 years
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Ivanova
Olga Vladimirovna
Radiotherapist
Magdiev Arslan Khulatdaevich
Experience 14 years
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Magdiev
Arslan Khulatdaevich
Surgeon, oncologist, phlebologist
Iluridze Georgy Davidovich
Experience 9 years
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Iluridze
Georgy Davidovich
Oncologist, traumatologist-orthopedist, surgeon
Alferov Anton Sergeevich
Experience 16 years
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Alferov
Anton Sergeevich
Leading urologist, andrologist
Gabaraev Alan Petrovich
Experience 13 years
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Gabaraev
Alan Petrovich
Urologist, andrologist
Nemenov Alexander Alexandrovich
Experience 7 years
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Nemenov
Alexander Alexandrovich
Urologist, oncologist (oncourologist)
Melkonyan Lia Eduardovna
Experience 13 years
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Melkonyan
Lia Eduardovna
Oncologist, oncologist-mammologist, surgeon, radiologist, ultrasound diagnostician
Sokorutov Vasily Ivanovich
Experience 22 years
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Sokorutov
Vasily Ivanovich
Oncologist
Ivanov Alexey Mikhailovich
Experience 22 years
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Ivanov
Alexey Mikhailovich
Oncologist
Mashkey Maria Igorevna
Experience 2 years
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Mashkey
Maria Igorevna
Oncologist
Dubinina Yulia Nikolaevna
Experience 13 years
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Dubinina
Yulia Nikolaevna
Oncologist, hematologist
Ilyukhov Alexey Nikolaevich
Experience 23 years
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Ilyukhov
Alexey Nikolaevich
Oncologist
Zakharova Maria Alexandrovna
Experience 5 years
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Zakharova
Maria Alexandrovna
Oncologist-mammologist, plastic surgeon
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Achba Maya Otarovna

Anton Sergeevich received me earlier than the appointed time, conducted all the necessary research, politely and easily explained certain aspects that interested me. The doctor gave the impression of being a very professional specialist.
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Alferov Anton Sergeevich

A wonderful doctor!!! I've told you everything, explained it! Helped!
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About doctor:

Alferov Anton Sergeevich

A very warm welcome, administrator Antonina, very attentive, patient and correct, makes out and charges with positivity! Dr. Ivanov Alexey Mikhailovich is attentive and friendly, Nurse Irina is in the treatment room, she is also very pleasant and helpful, overall, the clinic has a pleasant impression!!!
12.08.2026
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I would like to express my deep gratitude to the doctors: Morozova A.S. and Ivanov M.A. for high professionalism, literacy, sensitive and caring attitude towards patients..
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