Radioembolization for liver cancer

Radioembolization is a minimally invasive treatment for liver cancer. The basis of the procedure is the introduction of microscopic radioactive spheres directly into the blood vessels feeding the tumor. They contain radionuclides, such as Yttrium-90, which emit radiation that kills cancer cells.
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About the direction

In the context of oncological practice, aimed at treating cancer pathologies, it is noted that cancer cells demonstrate increased consumption of energy and nutrients compared to normal cells, which necessitates the creation of additional blood flows. In the context of embolization therapies, catheter angiography is used to target agents directly to tumor tissues.

Among the innovative methods, radioembolization stands out, using microspheres with radioactive Yttrium-90, which are sent to the affected area. This method allows you to effectively destroy cancer cells through radiation.

About the direction

Head of the Academician Lyadov Rehabilitation Center

Lyadov Konstantin Viktorovich
Lyadov Konstantin Viktorovich
Academician, professor, Doctor of Sciences, PhD
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The use of radioembolization covers the following areas:

  • Treatment of primary liver tumors, including Hepatocellular carcinoma and Cholangiocarcinoma.
  • Treatment of liver metastases from a variety of cancers, such as colorectal, breast and melanoma, especially those resistant to standard chemotherapy.

Radioembolization may be an alternative to surgery and chemoembolization under certain conditions, such as portal vein thrombophlebitis or the presence of large tumors. It may also be considered as a life-saving treatment.

Liver embolization for metastatic lesions is relevant when traditional chemotherapy is ineffective or unsuitable. This method can be integrated into complex treatment and also plays a key role in preparation for operations and organ transplants.

Carrying out treatment

Chemoembolization begins with the insertion of a catheter through a vessel in the groin area. This technique involves the use of narrow, flexible tubes to deliver radiopaque contrast material into the hepatic arteries. This approach allows you to accurately determine the location of the vessels feeding the tumor.

Tumor embolization involves two key steps, each of which takes about 7-10 days. At the first stage, detailed angiography is performed to mark the vessels. A radioactive tracer is then injected, which allows the required dosage of treatment to be assessed, eliminating the risk of damage to healthy tissue. This stage can be called "trial".

The second stage of liver radioembolization is the direct administration of Yttrium-90. This isotope, located in microspheres 20-30 microns in size, provides pinpoint radiation within a radius of up to 11 mm, destroying cancer cells while minimizing harm to healthy tissue.

The use of radioembolization is especially important for the treatment of primary and metastatic liver tumors. This method is widely used in leading clinics in Turkey, where it is recognized for its effectiveness and minimal risk of complications.

Helpful information

Description of the procedure

Liver chemoembolization is a complex medical process consisting of two main steps: angiography and a specialized radiation medicine scan, each of which takes approximately 2-3 hours. Typically, after completing these steps, patients are free from radiation exposure within 4-6 hours. In most cases, a one-day hospital stay is sufficient, and sometimes patients leave the hospital on the day of the procedure.

In the process of liver embolization chemistry, local anesthesia is usually used. At this point, patients lie on their backs, remaining motionless throughout the procedure. Pain levels are monitored to ensure patient comfort. After the procedure, serious complications occur extremely rarely, due to which recovery is quick: usually within 1-2 days, patients return to normal life. However, symptoms of fatigue, loss of appetite and nausea may occur in the first two weeks, which are controlled with standard medications. It is worth noting that the side effects differ significantly from those that occur with systemic chemotherapy.

Patients after chemoembolization can safely communicate with other people and use public transport, since the level of radiation after the procedure is minimal and does not pose a threat to others. It is still recommended to follow standard hygiene rules.

In certain cases, a temporary break from chemotherapy for several weeks may be necessary, which should be discussed with your doctor in advance. Sometimes radioembolization is performed in combination with chemotherapy.

The liver embolization procedure helps to reduce the volume of tumor formations, which in some cases opens the way for subsequent surgical intervention.

Criteria for prescribing the procedure

Preparation and criteria for deciding on radioembolization in the case of liver metastases begin with a thorough review of the patient's medical history. This process includes:

  • Diagnostic image of a liver tumor.
  • Conducting laboratory tests.
  • Analysis of the general physical condition of the patient.
  • Evaluation of current treatment.

In general, patients with extensive liver disease or advanced disease are not considered suitable candidates for this procedure.

The decision to use radioembolization in the treatment of liver metastases is the result of the joint work of an interdisciplinary group of oncology specialists. This procedure is performed by an experienced interventional radiologist with appropriate qualifications (eg CIRSE accreditation), while a radiation medicine expert plays a key role in determining safe levels of radiation exposure.

Preparation for the procedure

Before the procedure for removing metastases in the liver, you must:

  • Consult a qualified interventional radiologist.
  • Provide a complete medical history and information about any medications you are taking, including natural supplements.
  • Indicate the presence of allergic reactions.
  • You may need to temporarily stop taking some medications, such as anticoagulants.
  • Fast 6-8 hours before the procedure.

Important! Women should tell their doctor if they are pregnant before treatment.

Rehabilitation and risks from the procedure

During the rehabilitation period after chemoembolization, the patient is prescribed to donate blood for laboratory tests at the end of the second and fourth weeks. The obtained test data is transmitted to the treating doctor. You are also scheduled to see your doctor for a check-up at the end of the fourth week. Three months after the procedure, the patient will be re-evaluated, including scans and blood tests, to assess the effectiveness of the treatment and overall health. Depending on the indication, regular X-ray examinations may be ordered every 3, 6 or 12 months to monitor progress.

Potential risks of liver chemoembolization include:

  • Complications associated with angiography, such as bleeding in the groin area, blood clots, risk of infection.
  • Possible side effects include gastrointestinal ulcers, pancreas problems, pneumonia, liver abscess or liver failure.
  • The need for hospitalization in case of complications rarely occurs due to the qualifications of interventional radiologists.

It should be noted that radioembolization can be repeated in accordance with medical indications, especially if both lobes of the liver are affected. The chemoembolization procedure is a significant element in the complex treatment of liver cancer, effectively combined with other treatment methods, including surgery and standard chemotherapy.

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I would like to express my great gratitude to all the doctors and the manager of the cancer department. Professionals with a large letter that can be trusted and not worried about the right treatment. Personally, I would like to say thank you very much to my husband's doctor, the Earshova Xenia Igorene. Thank you very much for your professionalism, understanding, patience and support. A more literate, careful and sensitive doctor in this direction of medicine, I don't think you'll find. My sincere gratitude and respect for all the doctors involved in my husband's treatment. Thank you.
13.03.2026
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Doctor from God. Perfect, careful, excellent surgery, full answer to all questions.
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Udin Oleg Ivanovich

I would like to express my great gratitude to the doctor for the excellent surgery and follow-up. Anton Sergeyevich is a high-level professional, experienced, careful and sensitive doctor. Thank you!
05.03.2026
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I'm going to K+31 at Peskova Marina Sergeyevna's. The doctor is very competent, responsive and careful. The clinic is great. Reception takes place on time, without waiting and waiting. All staff leave a good impression. You forget the disease while you're in good hands.
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I express my sincere gratitude to Alferov Anton Sergeevich, the attending physician, for the individual treatment of each patient! It's a professional with a big letter! There's no complaint left to me! Beautiful, understandable specialist explains every stage of treatment. Thank you and I recommend!
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Good evening! I would like to express my great gratitude to Dr. Chichanova Tatiana Vladimirina for the spirit and literateness! A doctor who's in contact with a panic, and you're putting on the right hand! I've been looking at Chichanoa T.V. for about seven years, since she was working at the Petrov Gate, and I'm very happy that with her shift to West, she hasn't lost her doctor and continued to be here. Long and healthy years of life, Tatiana Vladimirna! Thank you!
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Tatiana Vladimirna Chičanov is a real professional of his case. Knowing, with the greatest professional circle, is very careful. I've been seeing her for years, I can only trust her. And, in addition, an amazing man, mental and delicate, which makes her a unique specialist, creating positive emotions and a climate of trust.
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I've been seeing T.V. Chichkanova regularly for several years. I always return to K+31 to see this doctor. Tatyana Vladimirovna always provides a thorough examination and is ready to answer my questions and explain everything I need to know in an accessible manner. She's always friendly and attentive.
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Excellent doctor. He removed a growth on my face, and it was done carefully, leaving almost no scar. He understands what's important to his patients :)
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