Vulvar Cancer: Symptoms, Diagnosis, and Treatment

Tumors of the external genitalia are rare, most often occurring after age 60. Vulvar cancer develops slowly and for a long time presents only with itching, often mistaken for irritation. With early treatment, the disease is highly treatable. The patient is managed by an oncologist in conjunction with a gynecologic oncologist.

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What is this?

This is a malignant tumor of the vulva—the area around the vaginal opening—most often squamous cell carcinoma associated with HPV or skin changes. This malignancy causes ulcers and lumps.

Characteristics of the disease

The main difference is accessibility for examination. Changes are visible, so vulvar tumors can be detected early.

How is it different from other tumors of the external genitalia?

Tumors in this area vary in origin. Cancer of the external genitalia includes lesions of the vulva, vagina, and perineum.

What is this?

Causes and risk factors for development

Causes and risk factors for development

The exact cause is unknown; the causes are usually infection-related and age-related.

Age-Related Changes

The disease most often occurs after menopause, when the skin thins.

Human Papillomavirus (HPV)

In some patients, the disease is associated with infection. HPV increases the risk, and a link between HPV and vulvar cancer has been proven in young women.

Precancerous Diseases

Cancer is preceded by precancerous changes. These include dysplasia and lichen sclerosus, which can be treated promptly.

Chronic Inflammatory Processes

Chronic itching and scratching damage the skin and increase the risk.

Symptoms

Symptoms

The early stages are subtle. Symptoms of vulvar cancer appear gradually and do not cause symptoms for a long time.

Early Signs

The first sign is usually persistent itching; the first symptoms of vulvar cancer include burning, discomfort, and a small lump or spot.

Late Symptoms

Later symptoms include a non-healing ulcer, bleeding, pain, and metastases to the inguinal lymph nodes—these signs of vulvar cancer should not be ignored.

When to see a doctor

Any persistent change in the skin of the vulva is a reason to get examined. You should make an appointment with an oncologist if you experience:

  • Long-term itching and burning
  • Lumps
  • Skin color changes
  • Ulcers that don't heal
  • Bleeding
  • Pain and discomfort

Don't delay your appointment if the change lasts longer than two to three weeks.

General information

Diagnosis

The examination is based on physical examination, vulvoscopy, and biopsy; the diagnosis of vulvar cancer is carried out in stages:

  1. Initial examination by an oncologist
  2. Vulvoscopy
  3. Vulvar biopsy of the affected area
  4. MRI or CT scan to assess the extent

The diagnosis is confirmed by tissue sampling; The methods are conveniently compared in the table.

Initial examination by an oncologist

The doctor evaluates skin changes, inguinal lymph nodes, and general condition.

Instrumental diagnostics

Vulvoscopy examines tissue under magnification, and MRI shows the depth of invasion.

Biopsy and morphological examination

A vulvar biopsy with morphological examination determines the tumor type. Histology clarifies the form.

Determining the stage of the disease

The choice between organ-preserving surgery and more extensive intervention depends on the stage.

Method Purpose of the study When used What it allows to detect
Vulvoscopy Detailed examination of tissues If changes are suspected Lesions
Biopsy Morphological verification If changes are suspected Tumor Tumor type, grade of differentiation
Pelvic MRI Prevalence assessment Before treatment planning Depth of invasion and lymph nodes

Our specialists emphasize the value of early treatment.

"In our practice, we regularly encounter situations where patients seek medical attention after symptoms have persisted for a long time. Early diagnosis significantly expands treatment options. Our approach is based on a comprehensive assessment of the patient's condition, a consultation, and the selection of an individualized approach."

Diagnosis

Modern Treatment Methods

The treatment plan depends on the stage and the patient's condition: vulvar cancer treatment most often begins with surgery.

Surgical Treatment

Surgery is the primary method. Surgical treatment for vulvar cancer removes the tumor within healthy tissue.

Organ-preserving surgeries

These interventions remove only early-stage tumors, preserving function.

Radiation therapy

Radiation therapy complements or replaces surgery: radiation therapy for vulvar cancer is used for advanced disease.

Chemotherapy

In advanced forms, chemotherapy enhances the effects of radiation.

Targeted and drug therapy

Systemic treatment—targeted and drug therapy—is used for advanced disease, taking into account the characteristics of the tumor.

Combination treatment regimens

A combination of surgery, radiation, and drugs provides treatment for vulvar tumors.

Modern Treatment Methods

How We Select Treatment

We select treatment strategies as a team, not individually.

The Role of the Specialist Panel

The panel—an oncologist, a gynecologic oncologist, a surgeon, and a radiation therapist—together selects a treatment plan.

Individualized Treatment Plan

Each patient has their own treatment plan: it takes into account the stage, tumor type, age, and organ preservation preferences.

How We Select Treatment

Recovery after treatment

After treatment, not only disease control but also quality of life is important.

Postoperative rehabilitation

Rehabilitation includes wound care, pain relief, and returning to normal activities.

Patient monitoring

After treatment, the patient remains under observation: follow-up care helps detect relapses early and includes:

  • Regular oncologist visits
  • Inguinal lymph node monitoring
  • Ultrasound or MRI if necessary
  • Evaluation of healing and function
  • Psychological support

Regular visits are especially important in the first years after treatment.

Prevention of complications

Complications Wound care, physical therapy, and attention to leg swelling prevent this.

Recovery after treatment

Prognosis

The prognosis largely depends on the stage at which treatment is initiated.

Factors Affecting Prognosis

The outcome is influenced by tumor size, depth of invasion, and lymph nodes; with early detection, the prognosis is favorable.

The Importance of Early Diagnosis

Early diagnosis of cancer increases the chances of a cure, so a timely consultation with an oncologist is important.

Prognosis

Prevention

The disease cannot be completely eliminated. However, it is possible to reduce the risk. Screening and monitoring by a gynecologist are especially important after menopause.

Risk Factor Control

HPV vaccination, smoking cessation, and treatment of precancerous changes help reduce the risk.

Benefits of Visiting a Specialized Cancer Center

This tumor requires experience and a well-coordinated team, and our center provides that approach. What the patient receives:

  • An interdisciplinary approach to treatment
  • Modern diagnostic methods
  • An individualized plan and specialist consultation
  • Organ-preserving techniques when indicated
  • Comprehensive support and rehabilitation
  • Monitoring according to clinical guidelines

This format increases the chances of preserving tissue and quality of life.

Answers to frequently asked questions

Below are frequently asked questions from patients.

What symptoms may indicate vulvar cancer?

The most common are itching, burning, a lump, a non-healing ulcer, and bloody discharge. Any persistent changes require examination.

Can vulvar cancer be detected early?

Yes. With regular checkups and timely treatment, the disease can be detected early.

What methods are used to treat vulvar cancer?

Depending on the stage, surgery, radiation, drug therapy, or a combination of these are used.

Is follow-up necessary after treatment?

Yes. Regular follow-up helps monitor the condition and detect changes early.

Vulvar cancer is curable, especially when caught early. If you are concerned about persistent itching, a lump, or other signs of vulvar cancer, schedule a consultation with an oncologist at K+31.

Our doctors

Merkulov Igor Alexandrovich
Experience 34 years
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Merkulov
Igor Alexandrovich
Deputy Chief Physician for Oncology, Oncologist
Ershova Ksenia Igorevna
Experience 23 years
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Ershova
Ksenia Igorevna
Head of department, oncologist
Abashin Sergey Yuryevich
Experience 43 years
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Abashin
Sergey Yuryevich
Head of oncology projects, oncologist
Balkarov Beslan Khasenovich
Experience 17 years
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Balkarov
Beslan Khasenovich
Surgeon, oncologist, acting head of the surgical department
Volkova Daria Mikhailovna
Experience 17 years
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Volkova
Daria Mikhailovna
Head of the Department of Radiation Therapy, Radiotherapist
Morozova Albina Soslanovna
Experience 18 years
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Morozova
Albina Soslanovna
Acting head of the department of antitumor drug therapy, oncologist
Chudnykh Sergey Mikhaylovich
Experience 42 years
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Chudnykh
Sergey Mikhaylovich
Rukovoditel Tsentra Endokrinologii I Korrektsii Metabolicheskikh Narusheniy
Glotov Egor Maksimovich
Experience 11 years
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Glotov
Egor Maksimovich
Thoracic surgeon
Khromov Roman Aleksandrovich
Experience 22 years
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Khromov
Roman Aleksandrovich
Urologist
Berestok Tatyana Sergeevna
Experience 11 years
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Berestok
Tatyana Sergeevna
Oncologist, Mammologist, Plastic Surgeon
Pereverzev Maksim Andreevich
Experience 11 years
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Pereverzev
Maksim Andreevich
Oncologist-Mammologist, Plastic Surgeon
Kalakutskaya Natalia Lvovna
Experience 28 years
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Kalakutskaya
Natalia Lvovna
Doctor-oncologist
Malygin Sergey Evgenyevich
Experience 31 year
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Malygin
Sergey Evgenyevich
Oncologist-mammologist, surgeon
Pshikhachev Ahmed Mukhamedovich
Experience 23 years
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Pshikhachev
Ahmed Mukhamedovich
Urologist, Oncologist
Shevchuk Alexei Sergeyevich
Experience 26 years
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Shevchuk
Alexei Sergeyevich
Oncogynecology consultant, obstetrician-gynecologist
Chichkanova Tatyana Vladimirovna
Experience 25 years
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Chichkanova
Tatyana Vladimirovna
Oncologist-mammologist, radiologist
Ovsiy Oksana Gennadievna
Experience 14 years
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Ovsiy
Oksana Gennadievna
Doctor-oncologist
Katz Ksenia Vladimirovna
Experience 12 years
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Katz
Ksenia Vladimirovna
Dermatologist, oncologist, cosmetologist
Korshikova Kamila Mukhtorovna
Experience 5 years
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Korshikova
Kamila Mukhtorovna
Radiotherapist
Ter-Arutyunyants Svetlana Andreevna
Experience 27 years
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Ter-Arutyunyants
Svetlana Andreevna
Radiotherapist, oncologist
Udin Oleg Ivanovich
Experience 32 years
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Udin
Oleg Ivanovich
Deputy chief physician for surgery, surgeon
Kogonia Lali Mikhailovna
Experience 52 years
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Kogonia
Lali Mikhailovna
Chemotherapist
Gomov
Mikhail Alexandrovich
Consultant in oncogynecology, obstetrician-gynecologist
Menkes (Ryabova) Yulia Alexandrovna
Experience 5 years
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Menkes (Ryabova)
Yulia Alexandrovna
Oncologist-chemotherapist
Grishin Igor Igorevich
Experience 33 years
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Grishin
Igor Igorevich
Obstetrician-gynecologist
Achba Maya Otarovna
Experience 18 years
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Achba
Maya Otarovna
Radiologist, ultrasound diagnostician, oncologist-mammologist
Lukyanenko Vladimir Alexandrovich
Experience 18 years
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Lukyanenko
Vladimir Alexandrovich
Oncologist-mammologist
Volenko Ivan Alexandrovich
Experience 15 years
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Volenko
Ivan Alexandrovich
Surgeon-oncologist-mammologist, plastic surgeon
Yakovleva Yana Sergeevna
Experience 8 years
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Yakovleva
Yana Sergeevna
Radiotherapist
Ivanova Olga Vladimirovna
Experience 26 years
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Ivanova
Olga Vladimirovna
Radiotherapist
Magdiev Arslan Khulatdaevich
Experience 14 years
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Magdiev
Arslan Khulatdaevich
Surgeon, oncologist, phlebologist
Iluridze Georgy Davidovich
Experience 9 years
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Iluridze
Georgy Davidovich
Oncologist, traumatologist-orthopedist, surgeon
Alferov Anton Sergeevich
Experience 16 years
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Alferov
Anton Sergeevich
Leading urologist, andrologist
Gabaraev Alan Petrovich
Experience 13 years
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Gabaraev
Alan Petrovich
Urologist, andrologist
Nemenov Alexander Alexandrovich
Experience 7 years
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Nemenov
Alexander Alexandrovich
Urologist, oncologist (oncourologist)
Melkonyan Lia Eduardovna
Experience 13 years
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Melkonyan
Lia Eduardovna
Oncologist, oncologist-mammologist, surgeon, radiologist, ultrasound diagnostician
Sokorutov Vasily Ivanovich
Experience 22 years
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Sokorutov
Vasily Ivanovich
Oncologist
Ivanov Alexey Mikhailovich
Experience 22 years
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Ivanov
Alexey Mikhailovich
Oncologist
Mashkey Maria Igorevna
Experience 2 years
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Mashkey
Maria Igorevna
Oncologist
Dubinina Yulia Nikolaevna
Experience 13 years
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Dubinina
Yulia Nikolaevna
Oncologist, hematologist
Ilyukhov Alexey Nikolaevich
Experience 23 years
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Ilyukhov
Alexey Nikolaevich
Oncologist
Zakharova Maria Alexandrovna
Experience 5 years
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Zakharova
Maria Alexandrovna
Oncologist-mammologist, plastic surgeon
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Achba Maya Otarovna

Anton Sergeevich received me earlier than the appointed time, conducted all the necessary research, politely and easily explained certain aspects that interested me. The doctor gave the impression of being a very professional specialist.
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Alferov Anton Sergeevich

A wonderful doctor!!! I've told you everything, explained it! Helped!
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About doctor:

Alferov Anton Sergeevich

A very warm welcome, administrator Antonina, very attentive, patient and correct, makes out and charges with positivity! Dr. Ivanov Alexey Mikhailovich is attentive and friendly, Nurse Irina is in the treatment room, she is also very pleasant and helpful, overall, the clinic has a pleasant impression!!!
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I would like to express my deep gratitude to the doctors: Morozova A.S. and Ivanov M.A. for high professionalism, literacy, sensitive and caring attitude towards patients..
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