Pyelonephritis - diagnosis and treatment of the kidneys

Pyelonephritis is an infectious and inflammatory kidney disease that affects the renal parenchyma, calyces, pelvis, and tubules. The inflammatory process is most often caused by Escherichia coli, Pseudomonas aeruginosa, staphylococci, and other microorganisms. The disease can be acute or chronic and can affect one or both kidneys.

Urologists at the K+31 Clinic perform a comprehensive diagnosis and develop an individualized treatment plan for each patient, using modern laboratory and instrumental examination methods.

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Causes and risk factors

The main cause of pyelonephritis is the penetration of pathogenic microorganisms into the kidney tissue. Infection enters the kidneys either ascending (through the ureters from the bladder) or hematogenously (through blood from other sites of infection).

Factors that increase the risk of developing pyelonephritis:

  • Impaired urine flow (congenital ureteral anomalies, postoperative complications)
  • Urolithiasis
  • Inflammatory processes of the pelvic organs
  • Enlarged prostate in men
  • Decreased immunity
  • Diabetes mellitus and other endocrine disorders
  • Pregnancy (the enlarged uterus compresses the ureters)
  • The presence of formations in the kidney area
  • Hypothermia
  • Bladder catheterization

Pyelonephritis is common in women More often due to anatomical peculiarities—a shorter urethra facilitates the rapid spread of infection. In men, the disease is more often diagnosed in old age due to urodynamic disturbances.

Causes and risk factors

Symptoms of pyelonephritis

Acute pyelonephritis

Acute pyelonephritis

The disease develops rapidly and is accompanied by severe intoxication:

  • Severe lower back pain (unilateral or bilateral)
  • Fever up to 39–40°C
  • Chills and profuse sweating
  • Loss of strength, headache
  • Nausea, progressing to vomiting
  • Cloudy and dark urine
  • Painful and frequent urination
  • Thirst, bloating

If left untreated, toxic shock syndrome may develop, with a sharp drop in blood pressure, tachycardia, and pale skin.

Chronic pyelonephritis

Chronic pyelonephritis

Often asymptomatic and discovered incidentally during examination for another reason:

  • Weakness, increased fatigue
  • Loss of appetite
  • Dull pain in the lower back
  • Frequent urination
  • Periodic increase in temperature to 37.2–37.5°C

Periodic exacerbations provoke tissue scarring, which eventually leads to chronic renal failure.

Diagnostics at the K+31 clinic

If pyelonephritis is suspected, you should consult a urologist or nephrologist. K+31 specialists prescribe a range of tests:

Diagnostics at the K+31 clinic
  • A general urine analysis reveals elevated white blood cell counts and bacteriuria.

  • Nechiporenko's urine test determines the extent of the lesion and possible complications.

  • Urine bacteriological testing identifies the pathogen and determines antibiotic sensitivity.

  • A complete blood count and biochemistry profile detect inflammation and assess kidney function (creatinine, urea)

  • Ultrasound of the kidneys and urinary tract – identifies parenchymal edema and structural changes.

  • Dopplerography assesses blood flow in the renal vessels.

  • CT or MRI scans — if necessary to clarify the diagnosis and rule out complications.

Treatment of pyelonephritis

The approach to therapy depends on the form and severity of the disease.

Conservative treatment

  • Antibacterial therapy is the mainstay of treatment. The drug is selected based on the results of a bacterial culture and susceptibility testing. Broad-spectrum antibiotics are prescribed until the results are available.
  • Detoxification therapy — intravenous fluid administration to reduce intoxication
  • Anti-inflammatory and analgesic agents — to relieve pain
  • Phytotherapy — as a supplement to the main course (herbal uroseptics)
  • Diet therapy — limiting salt and protein intake, avoiding alcohol and spicy foods; drinking plenty of fluids (1.5–2.5 liters of fluid per day)

Surgical treatment

Indicated for complicated cases: kidney abscess, carbuncle, apostematous nephritis, urinary tract obstruction. Urologists at K+31 perform minimally invasive interventions, including drainage of purulent foci and restoration of urine flow.

General information

Prevention

  • Timely and complete treatment of urinary tract infections (cystitis, urethritis)
  • Adequate fluid intake – at least 1.5 liters of clean water per day
  • Regular bladder emptying without prolonged urinary retention
  • Avoiding hypothermia
  • Monitoring diabetes and other chronic diseases
  • Annual preventive examination (kidney ultrasound, urinalysis)
  • Strengthening the immune system: a balanced diet, physical activity
Prevention of pyelonephritis

Advantages of treatment at K+31

  • Multidisciplinary approach – urologists, nephrologists, endocrinologists, and gynecologists work as a unified team.
  • Modern laboratory – test results are delivered promptly, including bacterial culture and sensitivity testing.
  • High-tech diagnostics – expert-class ultrasound, CT, and MRI machines.
  • Comfortable inpatient facilities – single-bed rooms for patients requiring hospitalization.
  • Individualized approach – each treatment plan is tailored to the specific needs of the individual patient.
Advantages of treatment at K+31

FAQ

Can pyelonephritis resolve on its own without treatment?

No. Acute pyelonephritis without adequate antibiotic therapy can lead to kidney abscess, sepsis, and other life-threatening complications. Chronic pyelonephritis, left untreated, leads to gradual destruction of kidney tissue.

Which doctor should I see if I suspect pyelonephritis?

A urologist or nephrologist. At the K+31 clinic, you can schedule an appointment with a specialist without a referral.

How long does treatment for pyelonephritis last?

The course of antibiotic therapy for acute pyelonephritis is 10-14 days. For chronic pyelonephritis, treatment may be longer, with repeated courses and ongoing monitoring.

Is hospitalization necessary?

Mild cases can be treated on an outpatient basis. Hospitalization is indicated for high fever, severe pain, complications, or if the patient is unable to take oral medications.

Is pyelonephritis dangerous during pregnancy?

Yes, pyelonephritis in pregnant women requires special attention and treatment under the supervision of a urologist and obstetrician-gynecologist. An untreated infection can affect the course of the pregnancy.

What diet should I follow for pyelonephritis?

A dairy-based, plant-based diet is recommended, limiting salt, spicy, fried, smoked foods, and alcohol. It's important to drink enough fluids—at least 1.5–2 liters per day (unless there are cardiovascular contraindications).

Our doctors

Andranovich Stanislav Valerievich
Experience 29 years
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Andranovich
Stanislav Valerievich
Urologist, ultrasound diagnostics doctor
Kotov Sergey Vladislavovich
Experience 22 years
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Kotov
Sergey Vladislavovich
Deputy chief physician of K+31 for urology, chief urologist of K+31, urologist-andrologist, oncourologist, doctor of medical sciences, professor
Sorokin Nikolay Ivanovich
Experience 24 years
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Sorokin
Nikolay Ivanovich
Head of the urology department, urologist, oncologist, oncosurgeon, doctor of medical sciences, professor
Kamalov Armais Albertovich
Experience 42 years
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Kamalov
Armais Albertovich
Chief consultant in urology, urologist, doctor of medical sciences, professor
Survillo Igor Igorevich
Experience 13 years
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Survillo
Igor Igorevich
Urologist
Tereshchenko Suren Alexandrovich
Experience 28 years
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Tereshchenko
Suren Alexandrovich
Doctor urologist-andrologist
Dzhabrailov Jabrail Abdulazizovich
Experience 25 years
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Dzhabrailov
Jabrail Abdulazizovich
Urologist, andrologist
Pshikhachev Ahmed Mukhamedovich
Experience 23 years
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Pshikhachev
Ahmed Mukhamedovich
Urologist, Oncologist
Gomberg Mikhail Alexandrovich
Experience 43 years
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Gomberg
Mikhail Alexandrovich
Dermatovenereologist
Valeev Danil Ravilovich
Experience 6 years
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Valeev
Danil Ravilovich
Urologist
Dzhalilov Dmitry Olegovich
Experience 17 years
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Dzhalilov
Dmitry Olegovich
Urologist
Alferov Anton Sergeevich
Experience 16 years
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Alferov
Anton Sergeevich
Leading urologist, andrologist
Gabaraev Alan Petrovich
Experience 13 years
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Gabaraev
Alan Petrovich
Urologist, andrologist
Nemenov Alexander Alexandrovich
Experience 7 years
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Nemenov
Alexander Alexandrovich
Urologist, oncologist (oncourologist)
Kosova Inga Vladimirovna
Experience 23 years
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Kosova
Inga Vladimirovna
Urologist
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Reviews

We turned to Dr. Anton Sergeevich Alferov on the issue of bladder dysfunction. The examination was carried out promptly and professionally! The diagnosis is a bladder tumor. The result of the surgical intervention is excellent! The team works professionally! The anesthesiologists are great!!!!! Thank you very much 31K West!!! Attentive and respectful attitude towards the patient! I wish there were more doctors like that!!!!
14.04.2026
Mihail K.

About doctor:

Alferov Anton Sergeevich

I would like to express my deep gratitude to Anton Sergeevich for his professionalism and humanity. Anton Sergeyevich successfully performed the operation (TOUR) for my father, who was in pain, and was always in touch during the treatment. We have never seen such a human attitude anywhere before, and we sincerely thank you for that. Such doctors are worth their weight in gold.
13.04.2026
Nikolay V.

About doctor:

Alferov Anton Sergeevich

Many thanks to Anton Sergeevich for his prompt help in solving the problem with urolithiasis. From the moment of examination to the operation - literally a few days, attentive and caring supervision, constant communication and reaction. Thank you for your work!
01.04.2026
Ruslan S.

About doctor:

Alferov Anton Sergeevich

A wonderful specialist. From the first minute, professionalism and confidence were felt. Thanks for the help!
30.03.2026
Dmitriy A.
Good afternoon! Dmitri Olegovic's great gratitude! A gracious, skilled consultation, and the most important thing is that there is no environment. To be able to take over the doctor's main merit!
14.03.2026
Ah. Valery Gennadjevic
It's great, thanks to the great doctors, the Denter of the MB, the SV. Doctors with a big letter. Valeria and Tatyana managers also responded. It's always fast, clear and unnecessary.
13.03.2026
Victor I.
I would like to express my great gratitude to the doctor for the excellent surgery and follow-up. Anton Sergeyevich is a high-level professional, experienced, careful and sensitive doctor. Thank you!
05.03.2026
Alexeiev S.M.

About doctor:

Alferov Anton Sergeevich

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