Pyelonephritis is an infectious and inflammatory kidney disease that affects the renal parenchyma, calyces, pelvis, and tubules. The inflammatory process is most often caused by Escherichia coli, Pseudomonas aeruginosa, staphylococci, and other microorganisms. The disease can be acute or chronic and can affect one or both kidneys.
Urologists at the K+31 Clinic perform a comprehensive diagnosis and develop an individualized treatment plan for each patient, using modern laboratory and instrumental examination methods.
The disease develops rapidly and is accompanied by severe intoxication:
If left untreated, toxic shock syndrome may develop, with a sharp drop in blood pressure, tachycardia, and pale skin.
Often asymptomatic and discovered incidentally during examination for another reason:
Periodic exacerbations provoke tissue scarring, which eventually leads to chronic renal failure.
If pyelonephritis is suspected, you should consult a urologist or nephrologist. K+31 specialists prescribe a range of tests:
A general urine analysis reveals elevated white blood cell counts and bacteriuria.
Nechiporenko's urine test determines the extent of the lesion and possible complications.
Urine bacteriological testing identifies the pathogen and determines antibiotic sensitivity.
A complete blood count and biochemistry profile detect inflammation and assess kidney function (creatinine, urea)
Ultrasound of the kidneys and urinary tract – identifies parenchymal edema and structural changes.
Dopplerography assesses blood flow in the renal vessels.
CT or MRI scans — if necessary to clarify the diagnosis and rule out complications.
The approach to therapy depends on the form and severity of the disease.
Indicated for complicated cases: kidney abscess, carbuncle, apostematous nephritis, urinary tract obstruction. Urologists at K+31 perform minimally invasive interventions, including drainage of purulent foci and restoration of urine flow.
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Causes and risk factors
The main cause of pyelonephritis is the penetration of pathogenic microorganisms into the kidney tissue. Infection enters the kidneys either ascending (through the ureters from the bladder) or hematogenously (through blood from other sites of infection).
Factors that increase the risk of developing pyelonephritis:
Pyelonephritis is common in women More often due to anatomical peculiarities—a shorter urethra facilitates the rapid spread of infection. In men, the disease is more often diagnosed in old age due to urodynamic disturbances.