An ectopic pregnancy is a pathological condition in which a fertilized egg implants and develops outside the uterine cavity, most often in a fallopian tube. Embryo growth can lead to fallopian tube rupture, internal bleeding, and other dangerous complications. The earlier an ectopic pregnancy is detected, the greater the chance of preserving reproductive health. After surgical removal of the fertilized egg, it is important to diagnose and determine the cause of the condition to prevent similar problems in the future.
An ectopic tubal pregnancy occurs when a fertilized egg implants outside the uterus. This most commonly occurs in the fallopian tubes, and less commonly in the ovaries, cervix, or abdominal cavity. This condition occurs in 2% of cases and poses a serious threat due to the high risk of internal bleeding.
In rare cases (less than 2%), the embryo can implant in atypical locations, posing a particular risk to the woman's health. An ovarian ectopic pregnancy occurs when fertilization occurs directly within the follicle and is characterized by early bleeding as early as 4-6 weeks. Cervical pregnancies, often associated with previous IVF or cesarean section, are dangerous due to massive bleeding and in most cases require emergency hysterectomy. Abdominal pregnancies are the most difficult to diagnose and can progress to late pregnancy.
Ectopic pregnancies are classified into several types, depending on the location of implantation of the fertilized egg outside the cervix. Tubal pregnancies are the most common in our clinic, accounting for approximately 98% of all cases. They are classified by the section of the fallopian tube: ampullary, isthmic, and interstitial. Each type of tubal pregnancy has characteristic clinical manifestations and risk factors.
Less common are atypical forms: cervical, abdominal, and ovarian pregnancies. These variants are particularly severe and carry a high risk of massive bleeding.
The following symptoms are typical of an early ectopic pregnancy:
If you notice any unpleasant symptoms, consult a doctor for a comprehensive examination.
Early ectopic pregnancies may present with nonspecific signs similar to those of a normal pregnancy, making diagnosis difficult. However, as the pathological process progresses, the clinical picture becomes more pronounced.
As the embryo develops in the fallopian tube, the following symptoms appear:
In cases of progressive tubal pregnancy, a gynecological examination at the clinic may reveal sharp pain when the cervix moves.
If the tube ruptures (usually between 6-8 weeks), the following symptoms appear:
There are 3 types of ectopic pregnancy:
In rare cases, cervical pregnancy occurs. It is characterized by the attachment of the egg in the cervix, a high probability of sudden bleeding due to the proximity of large vessels.
The table presents the types of ectopic pregnancy with a description of the features and possible risks.
| Type of pathology | Where the egg is attached | Features | Possible risks |
|---|---|---|---|
| Abdominal |
Organs of the abdominal cavity:
|
|
|
| Tubal | Falling tube |
|
|
| Ovarian |
|
|
|
| Cervical | Cervical canal (cervical canal) | Can be caused by abortions, cesarean sections, or fibroids |
|
Yes, it does. Women under 25 have a lower risk of abnormal pregnancy. Between the ages of 30 and 40, the risk increases approximately 2-3 times. After 40, the risk becomes even greater, especially in the presence of pelvic diseases or fallopian tube surgery.
Women over 35 who are planning a pregnancy are recommended to undergo a comprehensive examination, including a tubal patency check, hormonal status assessment, and a consultation with a reproductive specialist.
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Causes and risk factors of ectopic pregnancy
The main cause is a malfunction of the fallopian tubes. These hollow organs are lined with microscopic villi that help the egg enter the uterus. If their function is impaired, the egg attaches in the wrong place.
The egg's passage into the uterus occurs through the coordinated work of several systems. The villi of the fallopian tube capture the egg after ovulation, while microscopic cilia on the inner surface of the tube create a directed flow of fluid. Simultaneously, muscular contractions of the tube walls gently propel the egg forward.
The above processes are under hormonal control: estrogen increases ciliary activity and tubal contractility, while progesterone has the opposite effect. When this delicate mechanism is disrupted, the egg may become retained in the tube.
Factors that increase the risk:
The risk of ectopic pregnancy is also high in women who have previously had an ectopic pregnancy and in those who use intrauterine contraceptive devices.
Pathogenesis and mechanisms of occurrence
The pathogenesis of ectopic pregnancy is based on a complex disruption of the fallopian tube's transport mechanism. The fertilized egg is retained in the lumen of the tube, where the implantation process into the mucosa begins. The embryonic trophoblast actively penetrates the tube wall, producing proteolytic enzymes that destroy its layers—the mucous, muscular, and serous. As the fertilized egg begins to grow and develop, the tube stretches and thins, which can ultimately lead to rupture with massive bleeding.