Mean corpuscular hemoglobin concentration (MCHC)
When diagnosing various types of anemia, a complete blood count (CBC) is performed, where in addition to the main indicators, erythrocyte indices are also calculated, among which the most important are MCH, MCHC, RDW and a number of others
MCHC shows how saturated the erythrocytes are with hemoglobin. The norm for this parameter is 30-38 g / dl. Its increase is extremely rare and almost impossible due to the peculiarities of the chemical solubility of Hb. If the indicator is still increased, then most likely the analysis was performed incorrectly and it must be repeated. With a similar repeated result, the clinician must look for serious violations of the water-salt and acid-base balance.
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Mean corpuscular hemoglobin concentration (MCHC)
A decrease is typical for:
- Iron deficiency and sideroblastic anemia
- Thalassemia – a genetic disorder of hemoglobin protein synthesis
- Symptoms of pancreatitis (girdling painful sensations in the epigastrium, bloating, nausea after eating and subjective improvement during fasting)
- Other hemoglobinopathies (sickle cell anemia, methemoglobinemia, carboxyhemoglobinemia)
In general, MCHC plays a major role not only in the differential diagnosis of blood diseases, but also in assessing the reliability of the completed CBC. Therefore, the interpretation of the obtained values should only be done by a specialist doctor who can make the correct diagnosis or prescribe additional studies to exclude false results.
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