Treatment of Coronary Artery Disease (CAD)

Coronary artery disease (CAD) is a group of chronic conditions in which the heart muscle suffers from oxygen deficiency. This pathology occurs when the coronary arteries fail to provide sufficient blood flow to the myocardium. This state of oxygen deprivation is called ischemia. The main mechanism for the disease's development is atherosclerosis—the formation of cholesterol plaques on the walls of blood vessels, narrowing their lumen. During physical or emotional stress, the heart's need for nutrition increases, and narrowed arteries are unable to deliver blood. CAD is one of the leading causes of death worldwide, highlighting the need for timely diagnosis and treatment.

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Causes and risk factors of coronary heart disease

The main cause of coronary heart disease is atherosclerotic lesions of the coronary arteries. Cholesterol plaques form on the vessel walls, narrowing their lumen and impeding blood flow to the heart muscle, or myocardium. Another important cause can be coronary artery spasm or the formation of a thrombus that completely blocks the vessel. Any of these conditions leads to oxygen starvation of the myocardium and the development of ischemic processes.

Coronary heart disease has a chronic, progressive course. Hypertension, high cholesterol, diabetes, and smoking are predisposing factors for every patient. These factors accelerate damage to arterial walls and contribute to the growth of atherosclerotic plaques.

Coronary Heart Disease - Causes and Pathogenesis

Factors contributing to the development of coronary heart disease

Diagnosis of Coronary Heart Disease: ECG and Cardiac Ultrasound

The main cause of coronary heart disease progression is a combination of controllable lifestyle factors. There are also circumstances. Any patient can slow the progression of coronary heart disease by changing their habits. Here are the main risk factors for coronary heart disease:

  • Poor diet
  • High cholesterol
  • Hypertension
  • Diabetes
  • Overweight
  • Sedentary lifestyle
  • Smoking
  • Alcohol consumption
  • Stressful situations

Also, factors for coronary heart disease include: old age, male gender, and hereditary factors.

Causes of Coronary Heart Disease in Women and Men

Although coronary heart disease affects both sexes, its development and manifestations have significant gender differences. In men, this pathology is most often diagnosed between the ages of 40 and 55, often due to behavioral risk factors. Women before menopause have a significantly lower risk of developing ischemia due to the protective effects of female sex hormones, estrogens. These hormones maintain the elasticity of arterial walls and a favorable lipid profile. After hormonal changes, the incidence of the disease increases sharply, catching up with and sometimes exceeding male rates.

Classification of coronary heart disease

The term "ischemic heart disease" is a general term. It encompasses both acute and chronic pathological conditions. Currently, Russia uses a classification of coronary heart disease by clinical forms, each of which has independent significance due to the specific clinical manifestations, prognosis, and treatment tactics, as recommended in 1979 by a group of WHO experts.

Angina:

  • Stable angina (indicating the functional class)
  • Coronary syndrome X
  • Vasospastic angina
  • Unstable angina (progressive angina, new-onset angina, early post-infarction angina)
  • Myocardial infarction
  • Cardiosclerosis
  • Painless coronary heart disease

Sudden coronary death (primary cardiac arrest):

  1. Sudden coronary death with successful resuscitation
  2. Sudden coronary death (fatal outcome)

Diagnostics of coronary heart disease

To confirm the diagnosis of coronary artery disease, assess the extent of coronary artery damage, and determine further treatment, a cardiologist prescribes a comprehensive examination. This includes both laboratory tests and instrumental examinations:

  • Initial consultation with a cardiologist
  • ECG
  • Echocardiography (ultrasound examination of the heart)
  • Ultrasound Doppler (a method for vascular diagnostics) – allows for the assessment of atherosclerotic plaque development
  • Holter – a 24-hour ECG recording (can assess cardiac function under normal loads)
  • Stress tests
  • Final consultation with a cardiologist

Laboratory diagnostics

A critical step in diagnosis is laboratory assessment of risk factors. This is based on a lipid profile, which measures total cholesterol and its fractions. Lipid testing helps assess the risk of atherosclerosis, the main cause of ischemia. Blood glucose levels are also measured to detect diabetes. If acute coronary syndrome is suspected, markers of myocardial necrosis, such as troponin, are tested.

Instrumental diagnostics

An ECG (electrocardiogram) is a basic method for recording the heart's electrical activity, allowing for the detection of signs of ischemia or a previous heart attack. For a more detailed assessment, a Holter monitor is prescribed—a 24-hour ECG monitoring device that tracks the heart's function during the patient's daily life.

A cardiac ultrasound, or echocardiogram, visualizes the structure of the heart chambers and valves and evaluates their contractility. To induce and detect latent ischemia, a stress test is performed: an ECG is recorded during physical activity on a bicycle ergometer or treadmill.

General information

Symptoms of Coronary Heart Disease

The clinical presentation of coronary heart disease varies depending on its form. The main symptoms are related to insufficient blood supply to the heart muscle. The main manifestation of myocardial ischemia is angina – a feeling of tightness or burning behind the rib cage. This discomfort is usually triggered by physical activity or stress and subsides with rest. Patients often complain of pain radiating to the left arm, shoulder, or jaw.

Other common signs of the disease include shortness of breath, a feeling of incomplete inhalation, irregular heartbeats, and increased fatigue. It is important to note that coronary heart disease can develop without pain, manifesting itself only as general weakness, which complicates diagnosis.

Symptoms of Angina

Angina is the most characteristic sign of coronary heart disease. Its main symptom is a sensation of constriction, pressure, or burning in the chest. An attack is triggered by situations that increase the myocardium's need for oxygen, such as physical exertion or intense emotional stress. Pain often spreads to the left arm, shoulder, neck, and even the lower jaw. A distinctive feature of this condition is its rapid disappearance after cessation of exertion or with sublingual nitroglycerin.

Symptoms of Myocardial Infarction

Myocardial infarction is an acute form of ischemia that requires immediate medical attention. The main symptom is intense, piercing pain behind the breastbone that is not relieved by nitroglycerin and lasts more than 15–20 minutes. The pain may be accompanied by severe weakness, cold sweat, shortness of breath, and a strong sense of fear of death. With extensive myocardial damage, loss of consciousness is possible. The appearance of such symptoms is a reason to call an ambulance immediately.

Symptoms of Sudden Cardiac Death

Sudden cardiac death is the most serious complication of ischemia, often caused by acute occlusion of a large coronary artery. The condition develops rapidly, often without prior symptoms. The main signs are sudden loss of consciousness, cessation of breathing, and absence of a carotid pulse. The skin becomes pale or bluish, the pupils dilate and become unresponsive to light. This type of cardiac arrest requires immediate resuscitation, as irreversible changes in the brain occur within 5–7 minutes.

Pathogenesis of Coronary Heart Disease: Atherosclerosis and Thrombosis

Treatment methods for ischemic heart disease

Therapy at our clinic is based on:

  • Medication
  • Lifestyle changes and elimination (if possible) of risk factors

Medication

Medication therapy is aimed at improving the prognosis and relieving the symptoms of coronary heart disease. The doctor selects a combination of medications individually. The treatment regimen typically includes antiplatelet agents (such as aspirin) to prevent blood clots. A statin is prescribed to lower cholesterol levels and stabilize atherosclerotic plaques. Beta-blockers are used to reduce the heart's oxygen demand and control heart rate.

Surgical Treatment

When drug therapy is ineffective or vascular damage is critical, surgery is recommended. The goal of the surgery is to restore normal blood flow in the coronary arteries.

One method is balloon angioplasty with stenting. A catheter with a balloon is inserted through a puncture into the artery. The balloon is inflated at the site of the narrowing, widening the lumen. A stent—a special metal frame that supports the vessel walls—is then placed. For multiple or complex coronary artery lesions, coronary artery bypass grafting is performed, creating a bypass for blood flow using the patient's own blood vessel.

Treatment of Coronary Heart Disease in a Moscow Clinic

Rehabilitation after treatment for coronary heart disease

Successful treatment of coronary heart disease does not end with hospital discharge. A crucial stage is comprehensive rehabilitation aimed at preventing relapses and improving the prognosis. This includes drastic lifestyle changes: switching to a diet low in animal fats and salt, and completely quitting smoking.

Strict blood pressure monitoring and regular use of all prescribed medications are essential. Gradually increasing measured physical activity under the supervision of a specialist helps strengthen the heart muscle. Psychological support, which helps manage stress, also plays an important role.

Complications of Coronary Heart Disease

Failure to promptly and adequately treat the disease leads to the development of severe, life-threatening conditions. Chronic myocardial ischemia depletes its reserves, leading to complications such as heart failure—the heart's inability to pump blood effectively. Acute coronary artery thrombosis leads to myocardial infarction, the death of a section of the heart muscle. Another dangerous complication is the development of arrhythmias, including ventricular fibrillation, which can lead to sudden cardiac arrest.

Prevention of Coronary Heart Disease

The overall goal of ischemic heart disease prevention is the same for both patients with clinical manifestations or other atherosclerotic diseases and those at high risk: to reduce the risk of developing the main forms of ischemic heart disease or other atherosclerotic diseases, thereby reducing premature disability and mortality rates; and to improve survival. These recommendations define the goals of not only lifestyle changes but also the management of blood pressure, blood lipids, and diabetes through secondary and primary prevention of coronary disease.

Frequently asked questions and answers

Patients diagnosed with cancer often have many questions about their lifestyle, treatment, and prognosis. We've compiled answers to the most frequently asked questions to provide helpful information and clarity.

What are the appropriate blood pressure and pulse rates for coronary artery disease?

A doctor determines target values ​​for each patient with coronary artery disease. In most cases, blood pressure should be maintained below 130/80 mmHg. The optimal resting pulse rate is typically 55–60 beats per minute. Achieving these values ​​helps reduce the strain on the heart and improve the prognosis.

What should I avoid with coronary artery disease?

Patients with coronary artery disease should strictly avoid smoking and excessive alcohol consumption. Intense physical activity without prior preparation, as well as emotional stress, should be avoided. It is not recommended to stop or change the dosage of prescribed medications on your own.

How long can a person with coronary artery disease live?

The prognosis depends on many factors: the type of disease, the extent of vascular damage, the presence of complications, and, most importantly, adherence to all doctor's recommendations. Modern therapy and lifestyle changes can significantly slow the progression of the disease. Many patients, when following all recommendations, live long and full lives.

What parameters should be monitored in coronary heart disease?

Every patient should regularly monitor several important parameters. First and foremost, these are blood pressure and heart rate (pulse), which should be measured daily. Monitoring cholesterol and blood sugar levels is also important, and should be done as prescribed by a doctor.

Our doctors

Ryabenkova Olga Vladimirovna
Experience 24 years
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Ryabenkova
Olga Vladimirovna
Deputy chief physician for the organization of inpatient care, acting head of the cardiology department
Kambegova Albina Azamatovna
Experience 25 years
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Kambegova
Albina Azamatovna
Leading specialist in cardiology, cardiologist
Adjiev Renad Nadzhievich
Experience 18 years
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Adjiev
Renad Nadzhievich
Doctor-cardiologist, doctor of X-ray surgical methods of diagnosis and treatment
Tipteva Tatyana Alekseevna
Experience 15 years
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Tipteva
Tatyana Alekseevna
Cardiologist, physician of functional diagnostics
Dicker Gennady Mikhailovich
Experience 25 years
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Dicker
Gennady Mikhailovich
Leading Cardiologist
Goryunova Tatiana Vyacheslavovna
Experience 26 years
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Goryunova
Tatiana Vyacheslavovna
Leading cardiologist, functional diagnostics physician
Fomchenkova Oksana Ivanovna
Experience 30 years
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Fomchenkova
Oksana Ivanovna
Cardiologist
Starosvetskaya Victoria Grigoryevna
Experience 18 years
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Starosvetskaya
Victoria Grigoryevna
Cardiologist, functional diagnostics physician
Chapsurkaeva Berlant Uvaisovna
Experience 8 years
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Chapsurkaeva
Berlant Uvaisovna
Cardiologist
Mikhaylichenko Sergei Igorevich
Experience 16 years
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Mikhaylichenko
Sergei Igorevich
Cardiologist, arrhythmologist
Yurchikov Vadim Olegovich
Experience 9 years
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Yurchikov
Vadim Olegovich
Cardiologist
Kokaeva Izolda Omarovna
Experience 6 years
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Kokaeva
Izolda Omarovna
Cardiologist
May Karolina Marlenovna
Experience 14 years
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May
Karolina Marlenovna
Head of the clinical diagnostic center, cardiologist, functional diagnostics physician
Buzakova Nadezhda Igorevna
Experience 8 years
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Buzakova
Nadezhda Igorevna
Cardiologist
Tsadaeva Malika Sultanovna
Experience 6 years
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Tsadaeva
Malika Sultanovna
Cardiologist
Melnikova Elizaveta Sergeevna
Experience 9 years
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Melnikova
Elizaveta Sergeevna
Cardiologist
Gedgafova Svetlana Yurievna
Experience 29 years
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Gedgafova
Svetlana Yurievna
Cardiologist, functional diagnostics doctor
Dinevich Ekaterina Olegovna
Experience 4 years
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Dinevich
Ekaterina Olegovna
Cardiologist
Tengizova (Lavrentieva) Irina Alekseevna
Experience 3 years
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Tengizova (Lavrentieva)
Irina Alekseevna
Cardiologist, functional diagnostics doctor
Savinkova Ekaterina Aleksandrovna
Experience 15 years
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Savinkova
Ekaterina Aleksandrovna
Cardiologist, functional diagnostics doctor, ultrasound diagnostics doctor
Guchaeva Dinara Anzorovna
Experience 13 years
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Guchaeva
Dinara Anzorovna
Cardiologist
Arakelyan Arsen Samvelovich
Experience 6 years
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Arakelyan
Arsen Samvelovich
Cardiologist, general practitioner
Samokhin Nikita Valerievich
Experience 8 years
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Samokhin
Nikita Valerievich
Cardiologist, functional diagnostics physician
Shemenkova Victoria Sergeevna
Experience 12 years
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Shemenkova
Victoria Sergeevna
Head of the therapy department, general practitioner, cardiologist, functional diagnostics physician
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I was treated by cardiologist Nadezhda Igorevna Buzakova in January 2026. She is a competent and attentive specialist. Together with her colleagues, she quickly identified the cause of my condition, restored my heart function, and returned me to a full, active life. The doctor is available 24/7, for which I am very grateful.
27.01.2026
K. Alexander Fedorovich
I am grateful to Tatyana Alekseevna for a very attentive and thoughtful appointment, where the doctor took into account both heredity and the history of clinical manifestations related to hematology and gynecology, as well as for such a competent approach to prescribing additional tests, analyzing the results, and for her treatment recommendations!
23.01.2026
H. Inessa Alexandrovna
A truly professional approach. He made a course correction based on the survey data, discussed the possibilities and assumptions, and provided a justification.
22.01.2026
N. Vladimir Viktorovich
A very attentive, thoughtful, knowledgeable, and professional doctor. During the appointment, she asks patients questions not only about the specific problem they've encountered, but also about a much deeper and more comprehensive approach to understanding the cause-and-effect relationship of their illness and prescribing the most effective treatment. A huge advantage is that she can perform necessary tests (such as a cardiac ultrasound) and analyze the results during the appointment. During the appointment, the doctor truly communicates with the patient, rather than simply filling out computerized forms. After the appointment, Ekaterina Alexandrovna has no doubts about the effectiveness and positive results of the treatment she developed. I express my deepest gratitude to the doctor!
21.01.2026
B. Natalia Alekseevna
I really liked the doctor. He explained everything.
15.01.2026
K. Sergey Stenlivich
The doctor is attentive and consistent in his approach to my problem.
15.01.2026
M. Sergey Vyacheslavovich
Not only the diagnosis, but also the prescription helped!
13.01.2026
P. Yuri Anatolyevich
Excellent and attentive cardiologist!
04.01.2026
K. Vladislav Viktorovich
I came to Izolda Omarovna with high cholesterol and suspected mitral valve prolapse. I received top-notch care and answers to all my questions (even the silly ones!). I will continue to see her exclusively. Thank you!
12.12.2025
A. Dmitry Alekseevich

About doctor:

Kokaeva Izolda Omarovna

Excellent doctor, answered all questions.
12.12.2025
Z. Vasily Nikolaevich
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