Coronary artery disease (CAD) is a group of chronic conditions in which the heart muscle suffers from oxygen deficiency. This pathology occurs when the coronary arteries fail to provide sufficient blood flow to the myocardium. This state of oxygen deprivation is called ischemia. The main mechanism for the disease's development is atherosclerosis—the formation of cholesterol plaques on the walls of blood vessels, narrowing their lumen. During physical or emotional stress, the heart's need for nutrition increases, and narrowed arteries are unable to deliver blood. CAD is one of the leading causes of death worldwide, highlighting the need for timely diagnosis and treatment.
The main cause of coronary heart disease progression is a combination of controllable lifestyle factors. There are also circumstances. Any patient can slow the progression of coronary heart disease by changing their habits. Here are the main risk factors for coronary heart disease:
Also, factors for coronary heart disease include: old age, male gender, and hereditary factors.
The term "ischemic heart disease" is a general term. It encompasses both acute and chronic pathological conditions. Currently, Russia uses a classification of coronary heart disease by clinical forms, each of which has independent significance due to the specific clinical manifestations, prognosis, and treatment tactics, as recommended in 1979 by a group of WHO experts.
Angina:
To confirm the diagnosis of coronary artery disease, assess the extent of coronary artery damage, and determine further treatment, a cardiologist prescribes a comprehensive examination. This includes both laboratory tests and instrumental examinations:
A critical step in diagnosis is laboratory assessment of risk factors. This is based on a lipid profile, which measures total cholesterol and its fractions. Lipid testing helps assess the risk of atherosclerosis, the main cause of ischemia. Blood glucose levels are also measured to detect diabetes. If acute coronary syndrome is suspected, markers of myocardial necrosis, such as troponin, are tested.
An ECG (electrocardiogram) is a basic method for recording the heart's electrical activity, allowing for the detection of signs of ischemia or a previous heart attack. For a more detailed assessment, a Holter monitor is prescribed—a 24-hour ECG monitoring device that tracks the heart's function during the patient's daily life.
A cardiac ultrasound, or echocardiogram, visualizes the structure of the heart chambers and valves and evaluates their contractility. To induce and detect latent ischemia, a stress test is performed: an ECG is recorded during physical activity on a bicycle ergometer or treadmill.
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Causes and risk factors of coronary heart disease
The main cause of coronary heart disease is atherosclerotic lesions of the coronary arteries. Cholesterol plaques form on the vessel walls, narrowing their lumen and impeding blood flow to the heart muscle, or myocardium. Another important cause can be coronary artery spasm or the formation of a thrombus that completely blocks the vessel. Any of these conditions leads to oxygen starvation of the myocardium and the development of ischemic processes.
Coronary heart disease has a chronic, progressive course. Hypertension, high cholesterol, diabetes, and smoking are predisposing factors for every patient. These factors accelerate damage to arterial walls and contribute to the growth of atherosclerotic plaques.