Cortexil Plasma Therapy

Cortexil therapy is an innovative skin rejuvenation technique that stimulates collagen production and triggers regeneration processes at the cellular level. Unlike standard plasma therapy, Cortexil PRP successfully copes with age-related changes, acne, hair loss and other aesthetic problems.

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How Cortexil PRP Therapy Works

The principle of action of PRP Cortexil plasmolifting is based on the use of the patient's blood plasma enriched with platelets. The stages of treatment begin with the collection of venous blood in a small volume in a specialized Cortexil PRP1 container. Then the blood is placed in a centrifuge, where it is separated into three fractions:

  • The lower one contains red blood cells
  • The middle one contains white blood cells and platelets
  • The upper one contains a small amount of platelets

The PRP layer includes the most important elements: new plasma, growth factors and macrophages (active white blood cells with the potential for regeneration). This part is combined with normoplasma, creating a mixture for injection.

Cortexil plasma therapy is superior to standard therapy due to a higher level of viable plasmas - up to 1 million per 1 microliter, which provides a strong therapeutic effect.

After the introduction of Cortexil into the body, the plasmas activate a signal for recovery and begin to produce growth factors that stimulate:

  • Reproduction and growth of connective and cartilage tissue cells
  • Production of collagen, elastin and hyaluronic acid
  • Improvement of blood microcirculation
  • Normalization of metabolic processes

As a result, natural rejuvenation and tissue restoration occurs at the cellular level. The effect of the therapy increases over time and lasts up to two years.

How Cortexil PRP Therapy Works

Benefits of Cortexil plasma therapy

The main advantages of the Cortexil PRP plasma therapy method include:

  • High concentration of active platelets
  • Use of syringe tubes to extract the highest quality plasma
  • Use of a special centrifuge that guarantees optimal cell preservation
  • Use of the patient's own plasma, which minimizes the risk of allergic reactions
  • Minimal invasiveness, no long recovery period and significant side effects

The Cortexil procedure is used not only in cosmetology, but also in orthopedics, sports medicine, neurology and other fields.

General information about the procedure

Preparation for the procedure

Preparation for PRP includes a number of recommendations:

  1. Two weeks before the procedure, you must stop taking non-steroidal anti-inflammatory drugs
  2. 7-10 days before the procedure, it is recommended to start taking complex multivitamins
  3. Abide 1 day before the procedure

The procedure is performed 4-6 hours after eating. If it is scheduled for the morning, you are allowed to have a light breakfast. In the case of an evening session, a light lunch of fruits and vegetables is allowed. 12 hours before the procedure, you should refrain from heavy, fatty, spicy and salty foods, as they can negatively affect the quality of the blood and reduce the effectiveness of the therapy.

Cortexil Plasma Lifting Stages

The procedure consists of several stages:

  1. Blood sampling. A small volume of the patient's venous blood is collected (usually 15-30 ml). The blood is placed in a Cortexil PRP tube containing an anticoagulant based on sodium citrate and glucose. This composition prevents blood clotting and activates platelets in tissues
  2. Centrifugation. The tube with blood is placed in a Cortexil PRP centrifuge, specially designed for this technology. It creates the necessary centrifugal acceleration of 580G to maintain platelet activity and separate the blood into three layers
  3. PRP preparation. The Buffy Coat layer is removed from the tube, containing up to 9 million platelets per 1 microliter. It is mixed with normoplasma to achieve an optimal platelet concentration of 1 million per 1 microliter

The prepared plasma is injected into problem areas using thin needles or cannulas. The injection technique depends on the purpose of use and can vary from microinjections to linear or fan-shaped distribution.

Plasma therapy effect

After Cortexil PRP therapy, the patient receives:

  • Intensive skin restoration
  • Increased elasticity and tone
  • Reduction of fine and moderate wrinkles

Hair density after a course of plasma therapy increases by 30–40%, making this method an effective alternative to drug-based methods of combating hair loss. To achieve maximum effect, it is recommended to undergo a full course of 3–5 procedures with a break of 3–4 weeks. To maintain the result, it is worth conducting maintenance sessions 1–2 times a year.

Indications for PRP therapy

In cosmetology practice, Cortexil PRP therapy is recommended for the following indications:

  • Age-related skin changes (expression wrinkles, loss of elasticity)
  • Photoaging
  • Acne and traces of rashes
  • Hyperpigmentation
  • Couperose (dilation of small blood vessels)
  • Hair loss

The high concentration of platelets in Cortexil plasma creates a powerful restorative effect, which is important in the case of age-related slowdown in regeneration processes.

In the field of orthopedics and sports medicine, Cortexil PRP therapy is used to treat:

  • Arthrosis and arthritis
  • Ligament injuries and tendons
  • Muscle injuries
  • Tendon inflammation
  • Bursitis

The method is effective in rehabilitation after injuries and surgical interventions on joints. The introduction of platelet-rich plasma accelerates the tissue healing process and reduces pain.

PRP therapy has found application in trichology for the treatment of various forms of alopecia. Active growth factors stimulate hair follicles, improve microcirculation of the scalp, and promote hair strengthening and growth.

Recommendations after the procedure

In the first two days after the PRP procedure, it is necessary to:

  1. Avoid visiting saunas, baths, swimming pools and open water
  2. Abstain from intense physical activity and sports
  3. Abstain from alcohol
  4. Gently cleanse the skin with mild products and treat the injection sites with an antiseptic
  5. Postpone the use of decorative cosmetics for 2-3 days to prevent bacteria from getting into microtraumas on the skin
  6. Use sunscreens with a high SPF level before going outside
  7. Abstain from visiting a solarium
  8. Abstain from other cosmetic procedures

Following the recommendations after therapy prevents irritation and infection of the skin, creates optimal conditions for the action of the injected plasma.

For the best results of plasma therapy, it is important to follow a balanced diet rich in proteins and vitamins, drink at least 2 liters of water per day to stimulate metabolic processes in the skin and speed up its recovery.

Contraindications

Absolute contraindications to PRP include:

  • Systemic blood diseases (thrombocytopenia, anemia)
  • Acute infectious diseases, including hepatitis, HIV infection
  • Pregnancy, breastfeeding

In the presence of oncological diseases, the use of growth factors can stimulate the growth of tumor cells.

Relative contraindications to Cortexil PRP include:

  • Taking anticoagulants and antiplatelet agents
  • Autoimmune diseases
  • Tendency to form keloid scars
  • Mental disorders

In acute inflammatory processes or in case of exacerbation of chronic diseases, it is worth postponing the procedure until complete recovery or remission is achieved.

Answers to popular questions

Doctors from the K+31 clinic answered frequently asked questions about plasma therapy.

Can Cortexil plasma therapy be combined with other cosmetic procedures?

Cortexil PRP therapy can be combined with other cosmetic procedures: biorevitalization, mesotherapy, laser treatments. It is important to take breaks between sessions to enhance the regenerative effect. Biorevitalization is performed 2-3 weeks after plasma therapy, mesotherapy - 10-14 days, and laser procedures - 3-4 weeks.

Are there any seasonal restrictions for Cortexil plasma therapy?

Cortexil PRP therapy can be performed at any time of the year, since the method uses the body's own resources and does not include photosensitizing components. Spring and autumn are ideal times for procedures; in summer, it is necessary to intensively protect yourself from the sun; in winter, the procedure improves skin hydration and strengthens its protective properties.

Our doctors

Zakirova Gulnara Shokirovna
Experience 12 years
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Zakirova
Gulnara Shokirovna
Dermatologist, cosmetologist
Ivlieva Maria Georgievna
Experience 16 years
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Ivlieva
Maria Georgievna
Head of the department of dermatology and cosmetology, dermatologist, cosmetologist, trichologist
Miloradova Nataliya Nikolaevna
Experience 19 years
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Miloradova
Nataliya Nikolaevna
Cosmetologist, trichologist
Anoiko Olga Yuryevna
Experience 27 years
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Anoiko
Olga Yuryevna
Cosmetologist
Lebedinskaya Darya Alexandrovna
Experience 17 years
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Lebedinskaya
Darya Alexandrovna
Dermatologist, cosmetologist, trichologist
Kazantseva Ekaterina Victorovna
Experience 29 years
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Kazantseva
Ekaterina Victorovna
Dermatologist, cosmetologist
Katz Ksenia Vladimirovna
Experience 11 years
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Katz
Ksenia Vladimirovna
Dermatovenerologist, oncologist
Ilyina Ekaterina Vladimirovna
Experience 9 years
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Ilyina
Ekaterina Vladimirovna
Cosmetologist, dermatologist, trichologist
Andriyako Daria Alekseevna
Experience 12 years
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Andriyako
Daria Alekseevna
Dermatovenereologist, cosmetologist
Stepanova Yulia Sergeevna
Experience 15 years
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Stepanova
Yulia Sergeevna
Acting head of the department of dermatology and cosmetology, dermatologist, cosmetologist, trichologist
Korepanova Maria Viktorovna
Experience 29 years
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Korepanova
Maria Viktorovna
Dermatovenereologist
Marchenko Elena Viktorovna
Experience 12 years
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Marchenko
Elena Viktorovna
Head of the center for podology and mycology, dermatovenerologist, podologist, cosmetologist
Sukhanova Alexandra Sergeevna
Experience 8 years
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Sukhanova
Alexandra Sergeevna
Dermatologist, cosmetologist, trichologist
Muzhetskaya Anastasia Gennadievna
Experience 10 years
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Muzhetskaya
Anastasia Gennadievna
Dermatovenereologist, cosmetologist
Korolev Konstantin Kirillovich
Experience 8 years
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Korolev
Konstantin Kirillovich
Acting head of the dermatology department West, dermatovenerologist, cosmetologist, trichologist
Teplova Olga Igorevna
Experience 10 years
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Teplova
Olga Igorevna
Cosmetologist-esthetician, nurse in cosmetology
Chernova (Timoshevskaya) Inessa Andreevna
Experience 3 years
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Chernova (Timoshevskaya)
Inessa Andreevna
Dermatovenerologist, cosmetologist
Mavrova Irina Vasilievna
Experience 14 years
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Mavrova
Irina Vasilievna
Dermatovenerologist, cosmetologist
Golovkov Aleksandr Yurievich
Experience 14 years
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Golovkov
Aleksandr Yurievich
Cosmetologist, dermatovenerologist
Varaksa Natalia Valerievna
Experience 12 years
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Varaksa
Natalia Valerievna
Cosmetologist-esthetician
Gergova Diana Dzhemalovna
Experience 12 years
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Gergova
Diana Dzhemalovna
Dermatovenerologist, cosmetologist
Bakuridze Nino Alexandrovna
Experience 22 years
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Bakuridze
Nino Alexandrovna
Cosmetologist, dermatologist, preventive medicine doctor
Lipin Mikhail Nikolaevich
Experience 8 years
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Lipin
Mikhail Nikolaevich
Medical massage brother
Pakhomova Sofya Yurievna
Experience 26 years
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Pakhomova
Sofya Yurievna
Dermatologist, cosmetologist
Morozova Violetta Valerievna
Experience 6 years
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Morozova
Violetta Valerievna
Cosmetologist-esthetician
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Reviews 49

Excellent. He knows his business very well.
05.12.2025
K. Dmitry Vladimirovich
Thanks to the doctor, my face is getting better.
04.12.2025
L. Evgenia Alexandrovna
A very pleasant and competent doctor.
01.12.2025
R. Ekaterina
A very competent doctor, pleasant and polite reception. I am very pleased, thank you very much!!!
30.11.2025
A. Ekaterina Vasilievna
For the first time I was correctly diagnosed and the treatment helped.
23.11.2025
O. Aiza Idrisovna

About doctor:

Bobko Svetlana Ivanovna

Elena Viktorovna is a wonderful doctor! Knowledgeable, friendly, calm, and gets to the heart of the matter. I highly recommend her!
15.11.2025
Ch. Alexandra Mikhailovna
Extremely favorable impressions from the reception
09.11.2025
B. Elena Nikolaevna
I am simply delighted with the doctor - his attentiveness, professionalism and desire to help!
04.11.2025
Z. Zoya Fedorovna
A very attentive doctor, always ready to see a patient at a moment's notice. He helped resolve my issue quickly. I highly recommend him!
28.10.2025
D. Anna Sergeevna
Thanks to Alexandra for her professionalism!
28.10.2025
S. Natalia Alexandrovna
Excellent! The best doctor.
25.10.2025
G. Valeria Alekseevna
Excellent doctor, consulted on all issues
21.10.2025
G. Fedor Denisovich
Thank you to Elena Vladimirovna for her professionalism, attentive attitude, clear explanation of my problem, recommendations, and kindness. I am very pleased with the appointment!
16.10.2025
L. Marina Borisovna
Thank you to Ekaterina Viktorovna for the procedures and advice, for her exceptionally professional approach, and for explaining everything she did to my face!
10.10.2025
S. Natalia Igorevna
I'm very pleased with my visit to Tatyana Viktorovna, because all my questions and concerns were answered professionally and patiently. As a result, I have healthy and well-groomed skin.
06.10.2025
M. Flyura
A very competent doctor, she really helped me with my problem. Thank you.
30.09.2025
F. Daniil Viktorovich
Maria Viktorovna is a top-level specialist with an excellent attitude towards patients, effective diagnostics, and equally effective prescriptions and recommendations for treatment.
29.09.2025
E. Ivan Vladimirovich
A wonderful specialist, a true professional. Thank you very much for your work.
27.09.2025
Sh. Alevtina Vladimirovna
I have been a long-time patient of Alexandra’s, I respect her and thank her for her high level of professionalism!
21.09.2025
S. Natalia Alexandrovna
The most pleasant experience I've had with the doctor. Attentive, tactful, and professional.
20.09.2025
S. Stanka Alexandrovna
An excellent experienced doctor who knows how to establish contact with the patient, help and give recommendations for the future
14.09.2025
M. Gennady Nikolaevich
Maria Georgievna helped solve the problem with neoplasms on the face in one visit!
19.08.2025
K. Olga

About doctor:

Ivlieva Maria Georgievna

Khlunovskaya Anna Nikolaevna. Many thanks to the doctor for help. Excellent professional. I recommend. Sokolova Yana Olegovna. Professional. Many thanks. I recommend.
08.08.2025
Anonymously
This is not my first time with this doctor. I recommended him to my friends. All issues were resolved quickly and professionally. In addition, I really liked the communication with the doctor, everything was very friendly and understandable. Thank you very much!
05.08.2025
B. Sergey Valentinovich
I received a consultation on both dermatology and cosmetology. Very attentive.
02.08.2025
O. Daria Vladislavovna
I really liked the doctor, I really hope that he will help me figure out how to find a solution for treating my disease
23.07.2025
L. Evgenia Alexandrovna
Thank you, very nice and polite doctor. Explained everything clearly and calmly.
23.07.2025
R. Adelina Andreevna
I always feel comfortable at the reception, I go home in a good mood. Attentive and sensitive doctor.
17.07.2025
M. Elena Gennadievna
This is the best dermatologist I have ever met! Thank you very much, Yulia Sergeevna!
17.07.2025
A. Tatyana Vladimirovna
Attentive, delicate, truly systemically thinking doctor. Thank you for the diagnostics and procedure.
01.07.2025
E. Eva Vladimirovna
I am very pleased with the results of the procedures performed by the cosmetologist Vorobyeva Tatyana Viktorovna. She always explains in great detail, simply and clearly how the procedure will be carried out and what the result will be. Professionalism, warmth, pleasant communication and useful recommendations - you want to return to such specialists.
05.06.2025
Marina G.
I first came to see Inessa Andreevna two years ago and now I go exclusively to her. My problem for the last 15 years has been acne and, as a result, very visible pigmentation on my face in large areas. Inessa Andreevna is the first doctor (and I had several before her) who really brought me to a visible result in solving my problem. The rashes stopped, the spots were removed so much that I calmly began to allow myself to go without makeup. The treatment was chosen in such a way that while we were fighting pigmentation, the general condition of the skin improved. It became more even, dense and glowing. In general, if in a few words about Inessa Andreevna - a doctor who "hits" right on target, allows patients to be confident in the result, does not impose unnecessary things, and she herself is very beautiful, which I think is important for a cosmetologist).
22.05.2025
G. Vera
Inessa Vladimirovna is the doctor you go to for beauty, without fear and with 100% trust. Professionalism at the highest level. And a very sensitive approach.
18.05.2025
K. Irina Anvarovna
Inessa Andreevna is an amazing cosmetologist! The only cosmetologist I trust 100%, unconditionally, I know she won't give unnecessary advice, she won't hurt
14.04.2025
Sofia Z.
Dear Elena Viktorovna! I express my sincere gratitude for your amazing work. Here is my story. At the beginning of the year, I went to the clinic, made an appointment with Dr. Elena Viktorovna, for a consultation and treatment of chronic onychodystrophy and onychomycosis of the nails of the big toes. The nail on the toe of my left foot was in terrible condition, I was even ready for its surgical removal. The doctor immediately offered me a treatment system without the terrible removal: correction with a titanium thread, laser therapy, various external drugs and dietary supplements. I began to come to the procedures and follow all the necessary recommendations for treatment. I really like the laser heating procedure for nails, at first it was a little scary, and then even pleasant. The effect of the treatment did not appear immediately, barely noticeable and gradually as the nails grew. After six months, without exaggeration, a miracle happened: the nails acquired a normal, human appearance, and the former nightmare was left in the past. The treatment is still ongoing, but the positive result is obvious. My long-time dream that I will soon be able to walk barefoot openly is coming true. Elena Viktorovna, you are an excellent doctor and a wonderful person. Your main personal trait is your reverent care for the patient, and your professional traits are your golden hands, experience, iron patience and love for work. I am happy that I got treatment from you. I wish you career growth, success in professional development and studies. Thank you very much! In conclusion, I would like to write a few words to the heads of the clinic: Thank you for the good organization of the clinic, I wish you success and further prosperity. Please pay attention to the excellent work of Dr. Marchenko Elena Viktorovna. She is your golden employee! Such a doctor is the pride of the clinic. Please love, encourage and promote her. Sincerely, your client.
29.11.2024
Lapshinov Fedor
I express my admiration for the work of the cosmetologist Yegor Evgenievich Makhin. A qualified, competent cosmetologist, an excellent specialist and, what is no less important, a wonderful person. A worthy representative of the young generation of highly qualified specialists! Many thanks to the management of the clinic, in particular, the head of the department S.V. Pivovarova: it is very difficult to find and interest such wonderful doctors. Success and prosperity to you!
14.10.2024
Gombolevskaya Svetlana Leonidovna

About doctor:

Pivovarova Svetlana Victorovna, Makhin Egor Evgenievich

I am incredibly grateful to Tatyana Viktorovna for putting me into remission of long-term moderate acne; for almost 4 years I have not been bothered by rashes or pain and I have completely stopped using any foundation. Tatyana Viktorovna works for results, the tactics are cooperation with the patient, this includes advice, and answers to the strangest questions, and the coolest thing is that the doctor tells what should be done and why, explaining the processes. I am absolutely confident in my recommendations when I refer friends, girlfriends, acquaintances. The main thing for the patient to know is that they also need to make efforts and maintain discipline to achieve results. And Tatyana Viktorovna will definitely help
11.06.2024
Mikhailova Flura
Olga Yurievna, a very competent specialist and a Person with a capital P! Thank you very much for being you!
10.06.2024
Bogdan Andrey Vasilievich

About doctor:

Anoiko Olga Yuryevna

Very attentive and qualified doctor. I was very pleased with the reception.
03.04.2024
German Mikhail Mikhailovich
An excellent specialist and professional. Polite and courteous doctor. I have been visiting Lyubov Viktorovna for 4 months now. I have diabetes 2 and have foot problems. She helped me a lot. Thanks a lot!
26.02.2024
Victoria Nikolaevna Golovko

About doctor:

Arm Lyubov Viktorovna

Thank you very much, Ksenia Vladimirovna, for the high-quality and professional removal of keratomas. Very attentive, polite and pleasant to talk to. Gave clear advice necessary for treatment. The doctor saw me on time at the appointed time.
18.11.2023
Pogulyaa Galina Ivanovna

About doctor:

Katz Ksenia Vladimirovna

When I was young, I got a tattoo with my husband’s name. After the divorce, there was a desire to remove it. Clinic K+31 attracted my attention because they use modern and reliable equipment, and all the doctors are experienced and certified. At the preliminary consultation, the cosmetologist carefully examined the tattoo and said that the tattoo artist had introduced the pigment deeper than necessary, and this would complicate the process of removing it. It took me 8 procedures to completely cleanse my skin. The redness after the sessions went away within 4-5 days. The result met my expectations.
05.10.2023
Veronica

About doctor:

Ivlieva Maria Georgievna

I went to the clinic for a classic bikini. The professional work of the doctor pleases me. I was free after 20 minutes. There were no burns or painful sensations. The hairs began to fall out on their own on the 3rd day.
17.09.2023
Swede Maria
I decided to get rid of the tattoo any way I could. Safety and quality of service are always important to me, not price. The doctor at the K+31 clinic recommended removal with the PicoCare 450 laser. It took me 6 sessions to completely remove the image. Thank you for your help!
30.08.2023
Konstantin

About doctor:

Ivlieva Maria Georgievna

I would like to express my gratitude to Daria Alexandrovna Lebedinskaya! There is no discomfort after epilation. I was pleased with the delicacy of the work and painlessness. I have already done 3 procedures, we plan to do 3-4 more.
13.08.2023
Daria Kravtseva
Clinic K+31 was recommended to me by a friend. After looking at photos of other patients’ results on the website, I decided to remove the hated tattoo I got 8 years ago. Before the procedure, the doctor applied an anesthetic, so I did not experience much pain. The result pleased me.
23.07.2023
Victoria

About doctor:

Ivlieva Maria Georgievna

Many thanks to the cosmetologists K+31! I did 10 sessions of diode laser hair removal on the whole body. Totally removed hair from legs, arms, back and bikini area. I am very pleased. The skin is smooth, there has been no new hair at all for 2 months.
29.06.2023
Voronova Elena
Recently, I underwent a procedure of photorejuvenation and laser rejuvenation around the eyes by a cosmetologist Alexandra Sukhanova. I am very grateful to the doctor, excellent result. Under my eyes and on my right temple, I had small age spots, and so, all this disgrace disappeared, and there were fewer wrinkles under the eyes and it felt that the skin seemed to have become denser, dark circles under the eyes disappeared, the look became more open. The procedure itself was painless and everything went smoothly. Doctor is a professional in his field.
07.02.2023
Skryabina Irina Yurievna
I would like to express my deepest gratitude to Catherine. For a year of mesotherapy of the scalp, the hair began to recover. I went through 2 courses of 7-9 procedures and the difference between what was on my head (hair fell out after covid, problematic thyroid gland) and what is now huge. Hair restoration is a long, laborious process, and you don’t have to wait for a miracle right away. Mesotherapy is not a pleasant procedure. But you need to be patient and everything will work out. Ekaterina is a competent specialist, answers all questions, advises, encourages. Thank you so much)
12.12.2022
Tatiana
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Почему К+31?
К + 31 — full-cycle multidisciplinary medical centers, including the possibility of providing medical services of European quality level.
К + 31 — are leading doctors and diagnostics using high-tech equipment from world manufacturers (Karl Storz, Olympus, Siemens, Toshiba, Bausch&Lomb, Technolas, Zeiss, Topcon).
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Our clinics

K+31 on Lobachevskogo

st. Lobachevskogo, 42/4

+7 499 999-31-31

Subway
1
11
Prospect Vernadsky Station
By a car
Lobachevsky, we pass the first barrier (security post of the City Clinical Hospital No. 31), turn right at the second barrier (security post K+31)
Parking pass
Opening hours
Mon-Fri: 08:00 – 21:00
Saturday: 09:00 – 19:00
Sunday: 09:00 – 18:00
K+31 Petrovskie Vorota

1st Kolobovsky pereulok, 4

74999993131

Subway
9
Tsvetnoy Bulvar
10
Trubnaya
By a car
Moving along Petrovsky Boulevard, turn onto st. Petrovka, right after - on the 1st Kolobovsky per. Municipal parking
Opening hours
Mon-Fri: 08:00 – 21:00
Sat-Sun: 09:00 – 19:00
K+31 West

Orshanskaya, 16/2; Ak. Pavlova, 22

74999993131

Subway
3
Molodezhnaya
By a car
Moving along Orshanskaya street, we turn to the barrier with the guard post K+31. You do not need to order a pass, they will open it for you
Opening hours on holidays

01.11: 09:00—20:00

02.11—04.11: 09:00—18:00

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