DMAE Mesotherapy

DMAE mesotherapy is an advanced method of skin restoration in the presence of age-related defects. Dimethylaminoethanol activates the production of acetylcholine, which is responsible for muscle tone and skin elasticity. According to research, DMAE injection improves skin condition, provides lifting, and reduces the visibility of wrinkles. The cost of the procedure depends on the area being treated and the volume of the preparation - 2.5 or 5 ml.
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What is DMAE Mesotherapy?

DMAE is a strong antioxidant, actively used in cosmetology for skin rejuvenation. Mesotherapy with DMAE is an injection procedure aimed at renewing the skin.

The advantages of DMAE mesotherapy include:

  • Face contour correction. The DMAE procedure effectively strengthens the contours, making them more expressive
  • Fighting age-related changes. DMAE injections help smooth out fine wrinkles and fine lines
  • Tissue tightening effect. The drug improves muscle tone, reduces facial swelling, and enhances metabolism

The use of DMAE reduces sebum production, which helps in the fight against acne. In addition, the procedure reduces pigmentation, evens out skin tone, normalizes water balance and improves skin elasticity. Mesotherapy with DMAE is suitable for the face, neck, décolleté, abdomen and thighs. The course of treatment usually consists of 3-6 procedures. Between sessions of DMAE injections, it is necessary to take breaks of 7-10 days.

What is DMAE Mesotherapy?
Composition of DMAE injections

Composition of DMAE injections

DMAE injections include a combination of active ingredients that interact to improve skin quality. The main substances are dimethylaminoethanol, hyaluronic acid and organic silicon, which have an anti-aging effect. Let's take a closer look at these components of DMAE injections:

  • Dimethylaminoethanol (DMAE). The substance is a precursor of acetylcholine, a neurotransmitter that regulates muscle tone. In addition, it cleanses the body of lipofuscin, an aging pigment that accumulates on the human body with age.
  • Hyaluronic acid. Retains moisture in tissues, increases humidity and elasticity. Also helps restore the skin, makes it smoother and healthier
  • Organic silicon. Has antioxidant properties, maintains the health of cell membranes. In addition, it stimulates microcirculation and promotes the rapid removal of toxins from cells

Among the additional components in DMAE injections is vitamin C, which provides antioxidant protection and participates in skin regeneration. Plant extracts of Centella asiatica or ginseng are also used. They have an anti-inflammatory effect, stimulate the production of collagen and elastin fibers.

It is recommended to use DMAE in combination with a mesoroller or a device for fractional mesotherapy Dermapen Dr. Pen Ultima A6. To reduce pain, it is better to mix it with Procaine. To enhance the anti-aging effect, useful elements are added, and for skin tightening - organic silicon and KOSMO-TONUS with melilot.

General information about the procedure

Stages of DMAE mesotherapy

Therapy using DMAE procedures consists of several stages:

  1. Skin cleansing. The dermatologist removes makeup and other impurities to prevent bacterial contamination and improve the absorption of active components into the tissue. Then the skin is treated with an antiseptic
  2. Anesthesia. The doctor applies anesthetic cream and leaves it under the film for 15-20 minutes. It reduces pain, makes the process more comfortable for the patient
  3. Injection of the drug. The mesotherapeutic solution with DMAE is injected into the muscles using a thin 30-32 G needle

After DMAE, the skin is again treated with an antiseptic to minimize the risk of inflammation. It is possible to apply a soothing mask for rapid skin recovery after the procedure.

Procedure stages

Indications for DMAE mesotherapy

The DMAE procedure is performed in the presence of the following signs:

  • Deep and superficial wrinkles. DMAE reduces expression and age wrinkles, restores youth and freshness to the skin
  • Loss of elasticity. The procedure increases elasticity and gives the skin a toned look, which is important for women over 30
  • Blurred facial contours. Mesotherapy strengthens contours, prevents the development of ptosis
  • Pigmentation. DMAE lightens the skin, reduces the appearance of age spots
  • Scars and traces of acne. The procedure improves skin texture, reduces the visibility of post-acne
  • Dark circles under the eyes. Injections eliminate swelling, brighten the area around the eyes
  • Dryness and flaking. DMAE intensively moisturizes the skin, eliminates the feeling of tightness

The DMAE procedure is used to restore the skin after chemical peels or botulinum toxin injections. It also reduces the visibility of pores, which is useful for people with combination or oily skin.

Indications

Contraindications

The DMAE procedure is not performed in the presence of the following restrictions:

  • Oncology. May worsen the patient's condition after the procedure
  • Herpes in the active phase. Increases the likelihood of infection of the treated areas
  • Eczema, dermatitis, psoriasis during an exacerbation. Worsens the condition after the procedures
  • Hemophilia and other conditions affecting blood clotting. Lead to complications after the procedure
  • Pregnancy and lactation. The effect of the DMAE procedure on the fetus has not been fully studied
  • Allergic reactions to DMAE or other components of the mesococtail. Cause severe side effects

The DMAE procedure is also prohibited for those with liver, kidney, cardiovascular diseases, and epilepsy.

Contraindications

Advantages of DMAE injections

Advantage of DMAE Description
Fast effect The results are noticeable after the first procedure.
Minimal recovery period The procedure does not require long rehabilitation. Mild redness or slight swelling that occurs immediately after the injections usually disappears in a couple of hours. The patient can immediately return to normal life.
Safety DMAE is a natural substance.
Versatility Suitable for various areas of the body: face, neck, décolleté, hands.
Availability The procedure is available to all patients over 18 years of age.
Complex effect Improves skin tone, reduces wrinkles and tightens facial contours.
Prolonged result With regular courses, the rejuvenating effect accumulates, and the skin condition significantly improves.

DMAE is especially useful for people over 35. At 45–50 years of age and above, more treatments are required.

Advantages of DMAE injections

Answers to popular questions

Doctors at the K+31 clinic answered frequently asked questions about DMAE injections.

Is it possible to perform DMAE injections in the warm season?

Yes, it is possible. After the procedure in the summer, it is recommended to apply creams to protect the skin from sun rays.

What is important to do after the procedure?

The recovery period is quick and easy. During the week after DMAE injections, K+31 doctors recommend following a number of rules:

  • Abstain from using scrubs and cosmetics with aggressive components
  • Do not visit a bathhouse, sauna, or swimming pool
  • Abstain from tanning in a solarium or in the sun
  • Use sunscreen with SPF 30 or higher when going outside
  • Do not smoke or drink alcohol

Using decorative cosmetics is also prohibited.

Our doctors

Stepanova Yulia Sergeevna
Experience 15 years
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Stepanova
Yulia Sergeevna
Head of the department of aesthetic medicine and cosmetology
Zakirova Gulnara Shokirovna
Experience 13 years
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Zakirova
Gulnara Shokirovna
Dermatologist, cosmetologist
Ivlieva Maria Georgievna
Experience 17 years
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Ivlieva
Maria Georgievna
Head of the dermatology and cosmetology department, head of the dermatology and cosmetology department K+31 Petrovskie Vorota, leading dermatologist, cosmetologist, trichologist
Miloradova Nataliya Nikolaevna
Experience 20 years
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Miloradova
Nataliya Nikolaevna
Cosmetologist, trichologist
Anoiko Olga Yuryevna
Experience 28 years
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Anoiko
Olga Yuryevna
Cosmetologist
Lebedinskaya Darya Alexandrovna
Experience 18 years
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Lebedinskaya
Darya Alexandrovna
Dermatologist, cosmetologist, trichologist
Kazantseva Ekaterina Victorovna
Experience 30 years
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Kazantseva
Ekaterina Victorovna
Dermatologist, cosmetologist
Katz Ksenia Vladimirovna
Experience 12 years
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Katz
Ksenia Vladimirovna
Dermatologist, oncologist, cosmetologist
Ilyina Ekaterina Vladimirovna
Experience 10 years
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Ilyina
Ekaterina Vladimirovna
Cosmetologist, dermatologist, trichologist
Andriyako Daria Alekseevna
Experience 13 years
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Andriyako
Daria Alekseevna
Dermatovenereologist, cosmetologist
Korepanova Maria Viktorovna
Experience 30 years
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Korepanova
Maria Viktorovna
Dermatovenereologist
Marchenko Elena Viktorovna
Experience 13 years
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Marchenko
Elena Viktorovna
Head of the center for podology and mycology, dermatovenerologist, podologist, cosmetologist
Sukhanova Alexandra Sergeevna
Experience 9 years
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Sukhanova
Alexandra Sergeevna
Dermatologist, cosmetologist, trichologist
Vorobieva
Tatyana Viktorovna
Dermatologist, cosmetologist, trichologist, integrative and anti-aging medicine doctor
Muzhetskaya Anastasia Gennadievna
Experience 11 years
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Muzhetskaya
Anastasia Gennadievna
Dermatovenereologist, cosmetologist
Romanova
Olga Vladimirovna
Dermatovenerologist, cosmetologist, trichologist
Kolupaeva Alina Vasilievna
Experience 22 years
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Kolupaeva
Alina Vasilievna
Leading cosmetologist
Korolev Konstantin Kirillovich
Experience 9 years
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Korolev
Konstantin Kirillovich
Acting head of the dermatology department West, dermatovenerologist, cosmetologist, trichologist
Teplova Olga Igorevna
Experience 11 years
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Teplova
Olga Igorevna
Cosmetologist-esthetician, nurse in cosmetology
Chernova Inessa Andreevna
Experience 4 years
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Chernova
Inessa Andreevna
Dermatovenerologist, cosmetologist
Mavrova Irina Vasilievna
Experience 15 years
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Mavrova
Irina Vasilievna
Dermatovenerologist, cosmetologist
Imanova Karina Izmailovna
Experience 12 years
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Imanova
Karina Izmailovna
Cosmetologist-aesthetician, cosmetology nurse.
Sokolova Yana Olegovna
Experience 4 years
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Sokolova
Yana Olegovna
Dermatologist, cosmetologist, oncologist, trichologist
Golovkov Aleksandr Yurievich
Experience 15 years
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Golovkov
Aleksandr Yurievich
Leading dermatologist, cosmetologist
Varaksa Natalia Valerievna
Experience 13 years
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Varaksa
Natalia Valerievna
Cosmetologist-esthetician
Bakuridze Nino Alexandrovna
Experience 23 years
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Bakuridze
Nino Alexandrovna
Cosmetologist, dermatologist, trichologist, doctor of integrative preventive and anti-aging medicine
Lipin Mikhail Nikolaevich
Experience 9 years
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Lipin
Mikhail Nikolaevich
Medical massage brother
Pakhomova Sofya Yurievna
Experience 27 years
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Pakhomova
Sofya Yurievna
Leading dermatologist, cosmetologist
Morozova Violetta Valerievna
Experience 7 years
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Morozova
Violetta Valerievna
Cosmetologist-esthetician
Magomedova Luiza Abdullaevna
Experience 35 years
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Magomedova
Luiza Abdullaevna
Cosmetologist-esthetician, nurse in cosmetology
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Reviews

Many thanks to M.V. Korepanova!
30.04.2026
Tamara V.
I regularly go to Natasha's cleaners. And she's just wonderful! I've been to different specialists, but Natasha is the best. I go out after the procedures, as if the burden of unnecessary things has been lifted from me :)) and the face is always in perfect condition. After such purges, both to the feast and to the world. It feels like I've just had my pores cleaned, nothing pressed, but stroked with a feather)) at the same time, the wow effect: the face is clean, beautiful, without injuries! I highly recommend Natasha as a specialist and a true professional in her field!
28.04.2026
Nadezhda Ch.
A very pleasant and attentive doctor. Meticulous and thorough. She answered all the questions and gave detailed recommendations.
27.04.2026
Ilyana R.

About doctor:

Sokolova Yana Olegovna

Vorobyova T.V. is a very competent and experienced doctor.
24.04.2026
M. Had.
A wonderful specialist, all my skin problems were solved quickly. I had worries and concerns about the procedures for removing moles, but Elena Viktorovna dispelled them, I am very pleased with the result.
22.04.2026
Lyubov S.
I underwent the Indiba procedure, and I was absolutely delighted! After the first session, the result is noticeable: the skin has become more taut, fresh and well-groomed. The procedure is very comfortable, relaxing, and the effect is really impressive. I would also like to mention the professionalism and attentive attitude — everything was explained in detail, my peculiarities were taken into account, and the atmosphere itself was very pleasant and calm. I can confidently recommend this specialist to anyone who wants high-quality care and visible results.
18.04.2026
Elena K.
A very professional and attentive doctor, explains everything in detail and clearly. I recommend it!
08.04.2026
Irina P.

About doctor:

Sokolova Yana Olegovna

An excellent specialist. A very polite, calm, competent doctor.
31.03.2026
Olga K.
I wish to express my great gratitude, Olga Yurievna, for the highest professionalism, comprehensiveness, care and special treatment of patients with complex chronic diseases. Knowledge and experience enables a doctor to select and conduct procedures depending on the patient ' s current condition. It's always been a great outcome for over 10 years!
24.03.2026
Anna B.

About doctor:

Anoiko Olga Yuryevna

A wonderful doctor, very responsive. Just the nicest impression.
23.03.2026
I. Olga Nikolaevna
Почему К+31?
К + 31 — full-cycle multidisciplinary medical centers, including the possibility of providing medical services of European quality level.
К + 31 — are leading doctors and diagnostics using high-tech equipment from world manufacturers (Karl Storz, Olympus, Siemens, Toshiba, Bausch&Lomb, Technolas, Zeiss, Topcon).
К + 31 — is ethical. The staff of K+31 clinics maintain open relationships with patients and partners. An individual approach to each patient is the basis of our service standards.
К + 31 — is modernity. On call 24/7: call center operators will answer your questions at any time and book you an appointment with doctors. Contact us by phone, through the feedback form on the website and Max.

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Address K+31 on Lobachevskogo

st. Lobachevskogo, 42/4

Contacts

+7 499 999-31-31

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Mon-Fri: 08:00 – 21:00
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Opening hours on holidays

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09.05—11.05: 09:00—19:00

Address K+31 Petrovskie Vorota

1st Kolobovsky pereulok, 4

Contacts

+7 499 999-31-31

Opening hours

Mon-Fri: 08:00 – 21:00
Sat-Sun: 09:00 – 19:00

Opening hours on holidays

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09.05: нерабочий день

10.05—11.05: 09:00—18:00

Address K+31 West

Orshanskaya, 16/2; Ak. Pavlova, 22

Contacts

+7 499 999-31-31

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Mon-Fri: 08:00 – 21:00
Sat-Sun: 09:00 – 18:00

Opening hours on holidays

01.05—03.05: 09:00—18:00

09.05—11.05: 09:00—18:00

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