Oral lichen planus

Diseases of the oral mucosa often cause significant discomfort, as the oral cavity is involved in eating, speaking, and breathing. Among chronic pathologies, oral lichen planus occupies a special place – a condition that can go unnoticed for years or, conversely, cause severe pain.

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What is oral lichen planus?

Lichen planus (LP) is a disease of the skin and mucous membranes. Painful rashes (ulcers) appear in the mouth.

It is not infectious: it is not transmitted through kissing, sharing utensils, or household contact. A person becomes ill due to a weakened immune system: their body's cells begin to attack the mucous membrane epithelium.

Which areas of the mucous membrane are most often affected?

The pathological process is most often localized on the mucous membrane of the cheeks, especially in the posterior areas, closer to the molars. Lesions are also often found on the lateral surfaces of the tongue, gums, and, much less frequently, on the lips or palate. A characteristic feature of LP is its symmetry: if the characteristic white streaks on the oral mucosa appear on the right side, they are highly likely to appear on the left side as well.

How does it differ from stomatitis and other inflammations of the mucous membrane?

Unlike common aphthous stomatitis, which resolves within 7-10 days, lichen planus in the mouth is persistent. Stomatitis typically appears as a single, painful ulcer with surrounding redness, while lichen planus often presents as a network of whitish lines (Wickham's grid) that do not come off with a spatula. This is an important difference from candidiasis (thrush), where the white coating is easily removed, revealing reddened tissue.

The disease requires long-term observation, as it tends to have an intermittent course with periods of remission and exacerbations.

What is oral lichen planus?

Symptoms of oral lichen planus

Symptoms of oral lichen planus

Manifestations of the disease depend on its form, but there are classic signs that allow a doctor to suspect the diagnosis already at the first examination.

White reticular streaks and plaques on the mucous membrane

The main visual sign is small white or grayish-white papules. They intertwine, forming a pattern resembling lace, web, or mesh. These formations are either flat or slightly raised above the surface. In some cases, they can merge into dense white plaques resembling leukoplakia.

Burning, pain, discomfort when eating

In mild forms, the patient may not notice any changes at all, discovering the streaks accidentally in a mirror. However, as the disease progresses, a persistent burning sensation in the mouth develops, which intensifies with the consumption of acidic, spicy, salty, or hot foods. The mucous membrane becomes more sensitive, making every meal a torture.

Erosions, ulcers, redness, and swelling

In more severe cases, bright red areas—erosions—appear against the white mesh. These are areas where the protective epithelial layer has been destroyed. They can bleed at the slightest contact, such as when brushing your teeth. The surrounding tissue appears swollen and tense.

Causes and Risk Factors

Causes and risk factors

Modern medicine views LP as a multifactorial disease. A single, precise cause has not yet been established, but in most cases, it is related to a weakened immune system.

Immune and chronic inflammatory mechanisms

The main theory behind its development is immunological. For unknown reasons, T lymphocytes (immune cells) begin to recognize cells in the basal layer of the epithelium as foreign and destroy them. This causes chronic inflammation of the mucosa, which is self-perpetuated by the body.

Mucosa trauma, dentures, sharp teeth edges

Constant trauma to the mucosa is the main cause of the disease's spread.

Most often, this occurs due to:

  • Bad (or old) fillings with sharp edges
  • Metal crowns (cause microcurrents - galvanism)
  • Improperly fitted dentures
  • Biting cheeks or lips

Drug, contact, and lichenoid reactions

Sometimes, oral rashes are not true lichen, but a so-called lichenoid reaction to components of toothpastes, mouthwashes, or denture materials. Also, some medications for the treatment of hypertension, diabetes, or arthritis can cause mucosal damage as a side effect.

Stress, comorbidities, bad habits

Psycho-emotional stress often precedes the first episode of the disease or a relapse. Furthermore, the causes of lichen planus in the mouth are often associated with gastrointestinal diseases, liver diseases, diabetes, and hormonal changes. Smoking and alcohol are other triggers that can lead to the disease.

Forms of oral lichen planus

The clinical presentation of lichen planus is extremely varied. For ease of diagnosis, doctors distinguish several main forms, which can transition from one to another.

FormWhat it looks likeMain complaintsSeverity of discomfort
Typical reticularSmall white lines ("lace") on the cheeks and tongueUsually asymptomaticMinimal or absent
Erosive-ulcerativeBright red wounds against a background of white stripesSevere pain, burning, bleedingVery high
AtrophicRedness and thinning of the mucosa without ulcersSoreness, dryness, sensitivity to heatModerate
HyperkeratoticDense white plaques with clear edgesSensation of roughness, "excess tissue"Low, but requires monitoring

Typical reticular form

This is the most favorable variant. The patient notices a white mesh that is painless. The mucosa retains its normal color, and there is no swelling. There is only one treatment: observation and elimination of irritants.

Erosive-ulcerative form

The most severe manifestation. Ulcers that do not heal for a long time form on the mucous membrane. This erosive-ulcerative form requires active medical intervention, as the risk of secondary infection and complications is highest.

Atrophic form

With this form, the oral mucosa becomes thinner. It appears varnished and bright red. Patients complain that it is painful to eat even familiar foods, let alone seasonings.

Hyperkeratotic form

Characterized by pronounced keratinization. The lesions become hard, dry, and may resemble calluses. This is common in long-term smokers.

General information

Diagnosis of oral lichen planus

Diagnosis is the most important step, as it determines the treatment strategy. Self-diagnosis of oral lichen planus from photographs often leads to errors.

Mucosa Examination and Collection of Complaints

A dentist or dermatologist will conduct an examination under special lighting. It is important to assess not only the type of rash but also the condition of the teeth, the presence of dentures, and fillings. The doctor will definitely ask about the presence of systemic diseases and medications being taken.

Differential diagnosis

This is the process of ruling out similar diseases. A specialist needs to make sure it's not:

  1. Leukoplakia (a precancerous condition associated with keratinization)
  2. Candida (a fungal infection)
  3. Lupus erythematosus (a systemic disease with similar spots)
  4. Chronic mucosal injury

When a biopsy and histological examination are required

If standard treatment fails, a mucosal biopsy is performed. The doctor removes a fragment of the ulcer and performs a histological examination. There's no need to worry about pain: everything is done under local anesthesia.

This is the only way to detect LP and rule out malignancy.

Diagnosis of oral lichen planus

Treatment of oral lichen planus

Lichen planus is a chronic condition. It's impossible to completely eliminate the problem. Therefore, the main goal is to relieve pain, heal the ulcers, and achieve long-term remission.

A doctor cannot guarantee that the disease will not return, as lichen planus is not a virus, but an immune system issue.

Elimination of traumatic factors

This is the first and essential step. Without it, medications will only provide a temporary effect. Necessary:

  • Grind down sharp edges of teeth
  • Replace old, damaged fillings
  • Reline or replace dentures
  • Check the compatibility of metals in crowns

Local anti-inflammatory therapy as prescribed by a doctor

Treatment is based on topical agents: ointments, gels, and applications. A doctor may prescribe hormonal agents (corticosteroids) to suppress immune cell aggression, alcohol-free antiseptics, and healing oils. Keratoplasty (medications that accelerate epithelial regeneration) is sometimes used.

Systemic treatment as indicated

If topical agents are ineffective, systemic treatment for oral lichen planus is prescribed. This may include:

  • Medications that regulate the immune response
  • Vitamin complexes (especially vitamins A and E)
  • Sedatives to stabilize the nervous system

Oral hygiene and management of concomitant conditions

Professional hygiene and tartar removal reduce the microbial load on the inflamed mucosa. Sometimes, a consultation with a gastroenterologist and endocrinologist may be necessary. This is necessary to correct the functioning of internal organs.

Treatment of oral lichen planus

What to do and not do at home

The success of treatment also depends on how closely you follow your doctor's recommendations. The mucous membranes in people with LP are very fragile, so home care should be as gentle as possible.

Oral Hygiene for Sensitive Mucous Membranes

Use a soft-bristled toothbrush. Toothpaste should not contain sodium lauryl sulfate (SLS), menthol, cinnamon, or other pungent ingredients. After meals, rinse your mouth with warm boiled water or mild herbal infusions.

Diet for pain, burning, and erosions

A gentle diet should be followed: avoid hot and bitter foods and drinks.

You should also avoid citrus fruits, tomatoes, hot spices, tea, and coffee.

Recommended: porridge, mashed potatoes, pureed soups, soft cottage cheese, stewed vegetables. Food should be at room temperature or slightly warm.

Why self-medication can be dangerous

Many try folk remedies: cauterizing the lesions with alcohol, iodine, or pure celandine juice. This leads to severe chemical burns and can trigger tissue degeneration. Only a doctor knows how to treat lichen planus in the mouth, based on the specific form and stage of inflammation.

What to do and not do at home

Possible complications and prognosis

In most cases, oral lichen planus has a favorable prognosis if the patient follows treatment recommendations and does not self-medicate.

Chronic Course and Relapses

Relapses often occur in the fall and spring or during periods of severe fatigue. The main goal is to make these periods as infrequent and short as possible.

Risk of long-term non-healing erosions

Erosions can persist for months, creating a gateway for infection. Furthermore, constant inflammation alters the structure of epithelial cells.

Why is medical monitoring important?

Although the risk of malignancy (transformation into cancer) with lichen planus is low (approximately 1–2%), it does exist, especially with erosive forms in smokers. Regular checkups allow the doctor to notice suspicious changes early and take action.

Possible complications and prognosis

When to see a doctor urgently

Some symptoms require an immediate visit to a dentist or dermatologist. Don't delay an appointment if you experience:

  • Pain that makes it impossible to eat or drink
  • Bleeding from ulcers that won't stop
  • Induration at the base of an ulcer or white spot
  • Ulcers that hurt for more than two weeks
  • A white mesh has spread to healthy mucous membranes

If you're unsure which doctor to see, start with a general dentist or periodontist—these specialists most often deal with mucous membrane pathologies.

When to see a doctor urgently
Prevention of exacerbations

The main preventative measures are:

  • Oral self-examination in a mirror once a month
  • Timely dental treatment and prosthetics
  • Quitting smoking and spicy foods
  • Get adequate sleep, minimize stress, and treat chronic gastrointestinal diseases

The main goal is to boost immunity.

FAQ

Is it possible to permanently cure oral lichen planus?

A complete cure at the cellular level is not yet available to medicine, but it is possible to achieve sustained remission for decades, during which the patient remains free of any symptoms, and signs of the disease are only visible to a doctor during a thorough examination.

Is this disease contagious among family members?

No, LP is not contagious. It's an internal reaction of your immune system to external or internal irritants.

Should all crowns be removed if ringworm is detected?

Not necessarily. The decision to replace orthopedic structures is made by a doctor only if their connection to the development of the lesions is proven (for example, due to different metals or persistent trauma).
Conclusion

Oral lichen planus is always a sign of immune system problems. The key is not to panic or self-medicate. Early diagnosis of oral lichen planus, elimination of the underlying factors, and appropriate therapy are key to quickly resolving the problem.

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