Botulinum therapy in neurology

Botulinum therapy in neurology is a method of treating various neurological disorders using botulinum toxin (Botox).

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Botulinum toxin is a neuroparalytic poison consisting of highly toxic protein substances. The substance is toxic, but in minimal doses it has a therapeutic effect, as it blocks the transmission of nerve impulses and suppresses the production of neurotransmitters. This mechanism of action allows botulinum toxin to be used to treat various neurological disorders and diseases.

Used to treat conditions such as:

  • Spasticity is increased muscle tension resulting from disturbances in the central nervous system.
  • Various forms of dystonia are disorders of muscle tone that lead to involuntary movements or postures.

In addition, the method is used in the treatment of chronic migraines, hyperhidrosis (excessive sweating) and some other conditions.

Benefits for the patient

The main benefits of botulinum toxin treatment include the short duration of the procedure, only about 5 minutes, and effective results such as pain reduction and muscle relaxation. Other advantages:

Clinically proven high effectiveness and safety

Botulinum therapy is assessed as a highly effective and safe treatment method in neurology, which has been confirmed by many clinical studies. The effectiveness of botulinum toxin is manifested in the ability to reduce muscle spasm, reduce pain and improve motor function in patients with various neurological diseases. The safety of BTA is due to its specific action and strict dosage control, which minimizes the risk of side effects.

Lifelong injections if indicated

Botox in neurology, due to its effectiveness and safety, is especially valuable in the treatment of chronic diseases, since it allows patients to maintain a stable condition and control symptoms over a long period of time. An important feature of this method is the possibility of its long-term and sometimes lifelong use. for certain medical indications.

For example, for tension headaches, botulinum therapy relieves pain, significantly improving the quality of life. This condition is often associated with muscle tension in the head and neck. Regular use of botulinum toxin in neurology in these cases, it helps reduce the frequency and intensity of pain attacks, ensuring long-term remission.

Duration of effect from 4 to 6 months

One of the noticeable advantages of botulinum therapy is the duration of its effect. Typically, treatment results last from 4 to 6 months. This makes life easier for patients, as they do not have to frequently see a doctor and repeat procedures.

Versatility of the method

This treatment method is suitable for almost everyone, excluding only rare cases of individual intolerance to botulinum toxin. Thanks to this, a large number of patients with neurological disorders receive effective relief from the symptoms of their diseases.

Minimal risk of side effects

Botox treatment is characterized by a minimal risk of side effects. When they do occur, they are mild and temporary, making this method the preferred method.

In very rare cases, after administration of botulinum toxin, the following may occur:

  • Swelling.
  • Headache.
  • Allergic reactions.
  • Numbness.

And also pain at the injection site.

Sometimes the only treatment

In some clinical situations, botulinum therapy may be the only effective treatment method. This is relevant for patients with severe forms of muscle spasticity, for example:

  • For cerebral palsy.
  • After strokes.
  • For multiple sclerosis.

Also, botulinum therapy may be the only solution for chronic pain syndromes, including migraine or myofascial pain syndromes.

General information

The principle of action of botulinum toxin

The principle of action of botulinum toxin in therapy is based on several key aspects:

  • Direct effect on the transmission of nerve impulses. Botulinum toxin has a direct effect on the process of transmission of nerve impulses from nerves to muscles. This effect leads to a decrease in muscle contractility, which is especially important when treating conditions associated with increased muscle tone, such as spasticity.
  • Changing the functioning of receptors and blocking pain. Botulinum injections change the number of receptors in cells and block the production of substances responsible for pain. This leads to a decrease in pain intensity, which is especially important for patients suffering from chronic pain syndromes.
  • Effects on the central nervous system. The toxin is able to penetrate the central nervous system, affecting the activity of the nerve pathways of the brain. This can correct problems caused by conditions such as stroke or traumatic brain injury, which often lead to increased muscle tone.

As a result of the use of botulinum toxin, the following effects are achieved:

  • Relaxation of muscle tissue.
  • Decreased pain intensity.
  • Elimination of uncontrollable movements and seizures.
  • Relief of neurogenic inflammation.

These effects provide significant improvement in the condition of patients suffering from various neurological disorders.

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Indications

There are a number of neurological diseases for which botulinum toxin is indicated in medicine. Among them:

  • Chronic migraine. Characterized by frequent and intense headaches. Botulinum therapy reduces the frequency and intensity of attacks by acting on the muscles that cause tension and spasms.
  • Headaches with tension in the pericranial muscles. Botulinum therapy relaxes the muscles of the head and neck, reducing tension and relieving pain.
  • Facial pain, including dysfunction of the temporomandibular joint. The therapy reduces pain and muscle tension. Improves the functioning of the jaw joint.
  • Neuropathy of the facial nerve. For facial asymmetries and hyperkinesis, botulinum therapy restores symmetry and controls involuntary movements, thereby improving the appearance and functionality of the face.
  • Bruxism, or teeth grinding, leads to wear and tear in the jaw. Botulinum toxin therapy reduces muscle tension, which reduces grinding and associated symptoms.
  • Spasticity. Occurs after strokes, with cerebral palsy, head injury and multiple sclerosis, causing increased muscle tension. The therapy relaxes spastic muscles, improves motor function and relieves pain.
  • Dystonias, such as blepharospasm and oromandibular form, are characterized by involuntary muscle contractions. Botulinum toxin therapy reduces these contractions, relieving symptoms.
  • Hemifacial spasm, tics, myokymia. These conditions are manifested by involuntary contractions of the facial muscles. Botulinum toxin therapy helps control these contractions by reducing their frequency and intensity.
  • Sialorrhea (increased salivation). Hyperhidrosis (increased sweating). The therapy reduces sialorrhea and hyperhidrosis, blocks nerve impulses responsible for excessive secretion of saliva and sweat.
  • Myofascial pain syndromes. Characterized by pain in the muscles and surrounding tissues. Botulinum toxin therapy helps relax muscles, reduce pain and improve the functionality of the affected areas. This helps reduce tension and relieve chronic pain.
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Contraindications

  • the use of the drug is not recommended if there is an individual intolerance to BTA or any of its components, manifested in the form of allergic reactions;
  • Not suitable for patients with neuromuscular disorders, including myasthenia gravis and myasthenic syndromes.

The procedure cannot be done in case of inflammatory processes in the intended injection area, as well as in persons with blood clotting disorders, for example, hemophilia. All of these conditions can increase the risk of complications and worsen treatment outcomes.

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Preparation and diagnostics

Before starting treatment, the patient must undergo an examination so that the doctor can determine whether this method of treatment is suitable based on the individual characteristics of the patient and the nature of his disease. The main diagnostic methods include:

  • Magnetic resonance imaging (MRI)․
  • X-ray examination․
  • Ultrasound examination (ultrasound)․
  • Positron emission tomography (PET)․
  • Electroneuromyography (ENMG).

After receiving the examination results, the neurologist determines the duration of the course of treatment, calculates the required dose of the drug and draws up an individual plan for clinic visits.

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How the treatment procedure works

The botulinum therapy treatment process includes several stages, starting from diagnosis and ending with the botulinum toxin injection procedure itself.

The botulinum therapy procedure itself takes little time - usually no more than 5 minutes. It involves injecting botulinum toxin directly into the affected muscle. Botox is administered intramuscularly, sometimes under ultrasound guidance, to determine the injection site as accurately as possible.

During the procedure, electrical myostimulation can also be performed using a needle-electrode, which helps to consolidate the effect of Botox. This allows you to achieve relaxation of spasming muscles, relieve pain and cramps, and also stop neurogenic inflammation.

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After the procedure

After botulinum toxin injection, the patient can immediately return to their normal lifestyle, since botulinum therapy does not require a long recovery period. The effect of treatment begins to appear gradually and lasts for 3-6 months, depending on the individual characteristics of the patient’s body and the nature of the disease.

Botulinum therapy treatment is carried out on an outpatient basis in specialized medical centers, such as the K+31 clinic, where patients can receive consultations from specialized specialists and undergo all the necessary diagnostic procedures. This innovative treatment method combines high efficiency, safety and convenience for the patient.

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Our doctors

Nodel Marina Romanovna
Experience 32 years
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Marina Romanovna
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Tsareva Elena Vyacheslavovna
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Omarova Sabina Magomedovna
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Sabina Magomedovna
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Chernyakov Alexander Vladimirovich
Experience 32 years
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Alexander Vladimirovich
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Tikhonov Anton Vladimirovich
Experience 19 years
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Anton Vladimirovich
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Inna Sergeevna
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Remezova Tatyana Vasilevna
Experience 50 years
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Tatyana Vasilevna
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Mikhailova Natalia Alexandrovna
Experience 21 year
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Natalia Alexandrovna
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Vazyuro Ekaterina Viktorovna
Experience 8 years
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Botasheva Ladifa (Bella) Issaevna
Experience 16 years
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Soltakhanova Leila Omarovna
Experience 4 years
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Gorshkova Irina Alexandrovna
Experience 6 years
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Irina Alexandrovna
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Akulova Elena Mikhailovna
Experience 31 year
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Elena Mikhailovna
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Kuvaev Valery Alexandrovich
Experience 13 years
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Valery Alexandrovich
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Patrikeeva Alina Vladimirovna
Experience 26 years
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I'm so glad I had an appointment with Oksana Yuryevna. I felt like she was paying attention to my problem. She explained everything in detail, recommended tests, and prescribed treatment. Thank you! 12/30/25
30.12.2025
S. Vera Olegovna
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Wonderful doctor! She listened very carefully, reviewed other doctors' recommendations, and performed an examination! She made a prescription. Thank you so much!
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B. Irina Grigorievna
Excellent doctor, thank you very much!
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Ts. Evgeniy Vitalievich
Inna Sergeevna is the neurologist and professional I will recommend to my friends/colleagues.
16.12.2025
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About doctor:

Bogdanova Inna Sergeevna

She is a very, very, very best neurologist.
12.12.2025
V. Konstantin Sergeevich
I'm so glad I chose and visited Dr. Bogdanova. Inna Sergeevna is a highly skilled specialist. Throughout my entire appointment, I felt her attention to my problem. Communicating with her was incredibly easy; not everyone can accurately assess their condition. She guided the conversation with her questions and thoroughly examined the progression of my illness. She performed a series of diagnostic procedures, explaining what would happen and why they were necessary. I received an assessment of my condition and recommendations for further examinations. I'm confident that under her sensitive and experienced care, I will achieve results in my treatment. Thank you, Inna Sergeevna! I was impressed by the staff: the receptionists are attentive and friendly, creating a caring atmosphere.
10.12.2025
G. Elena Valerievna

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Bogdanova Inna Sergeevna

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K. Alexey Olegovich
Angelina Valerievna Tsindeliani is a wonderful doctor: professional, very attentive, and kind (which is extremely important!): she examined my 82-year-old mother with exceptional care and thoroughness and was incredibly helpful in every way, both professionally and personally! I wish you health, happiness, and all the best to this wonderful doctor!
28.11.2025
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Wonderful doctor! Very attentive, reviewed all my records and diagnoses, and performed a thorough examination! The visit left the best impression! Thank you, doctor!
27.11.2025
B. Irina Grigorievna
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