Analysis for antibodies to S1 protein - post-vaccination

At K+31 clinics, it is now possible to determine IgG antibodies (spike S1 protein) to the Sars-Cov-2 virus in blood serum by the method of enhanced chemiluminescence.

Why get tested?

The synthesis of S-protein in the body triggers an immune response - the production of antibodies. When they encounter an infection, they attack and destroy the virus.

The presence of antibodies against the S-protein indicates the presence of immunity: after a previous illness and resulting from vaccination. Using the test, you can determine the degree of effectiveness of vaccination against coronavirus.

Does this apply to all vaccines?

  • Vaccines available in the Russian Federation induce the synthesis of antibodies to the S-protein and its fragments.
  • The Sputnik V vaccine basically contains an adenovirus that delivers information about the viral S-protein to the cells. It is part of the spines (superficial processes) with which the coronavirus enters cells.
  • Vaccine prophylaxis with EpiVacCorona also induces the production of antibodies against the coronavirus S-protein.

What is the best time to get tested for S1 spike protein?

  • 5-6 weeks after 1st dose.
  • 10-14 days after the second.
  • It is available to conduct not only those who have been vaccinated, but also as confirmation of the transferred illness.

What will be the result?

The positivity coefficient (CP) shows how many times the concentration of antibodies exceeds the threshold value.