Cryo IVF protocols

In vitro fertilization is the process of conception in artificially created conditions, followed by implantation of embryos that have reached a certain stage of development into the uterine cavity. For only 30% of women, the first attempt ends with a long-awaited pregnancy. Cryoprotocol is an improved IVF method, the main difference of which is the transfer of frozen embryos. As a result, the chances of conception increase significantly and reach 70%.

The essence of the IVF method according to the cryoprotocol

krioeko1.jpg As a rule, several high quality embryos are obtained during the first in vitro fertilization attempt. Since it is not recommended to implant more than two embryos at the same time, the remaining ones are frozen for future use. In the clinic for reproductive medicine K + 31, only modern, safe cryopreservation technologies are used. Vitrification (quick freezing) makes it possible to avoid the crystallization of biological fluids and ensures their transition to a glassy state, which allows you to preserve the embryos for many years. Their survival rate after thawing is almost 100%, and further development does not differ from “fresh” embryos. Thus, cryoprotocol is usually applied after failed IVF.

Benefits of the IVF cryoprotocol

krioeko2.jpg Cryoprotocol is one of the most advanced and modern methods of infertility treatment. It is used when the usual IVF procedures fail, or the birth of a child is planned in the future. Cryo embryo transfer has the following advantages:

  • the ability to analyze and take into account the reasons for previous failures;
  • no need for hormonal stimulation;
  • the use of medications only for the preparation of the endometrium;
  • the ability to synchronize the state of the uterus with the stage of development of the embryo;
  • the absence of a follicular puncture procedure that injures the ovarian tissue;
  • embryo implantation can be carried out at a suitable moment for a woman;
  • relatively low cost due to the reduction in the number of drugs.

Cryoprotocols often end in pregnancy also because only the highest quality embryos are selected for freezing at the initial stage.

Preparation for IVF procedure according to cryoprotocol

krioeko3.jpg Preparation for the cryoprotocol at the K + 31 clinic includes the following steps:

  1. An experienced team of specialists, which includes a fertility specialist, geneticist and embryologist, carefully examines the reasons for a previous failed IVF in order to increase the likelihood of a successful repeat attempt.
  2. Examinations and analyzes are prescribed (additional and repeated (expired)).
  3. One of the most important steps is choosing the optimal moment for cryo transfer. For this, careful monitoring of the thickness of the endometrial layer in the uterine cavity is carried out. Taking into account individual characteristics and based on the test results, preparations containing estrogen and progesterone can be prescribed.

IVF cryoprotocol by day

There are three types of cryo-transfer, practiced at the K + 31 clinic:

  • in the natural cycle;
  • on HRT (hormone replacement therapy);
  • in a stimulated cycle.

The most gentle procedure for the female body is cryo in the natural cycle, since there is no need to take hormonal drugs. The doctor conducts ultrasound monitoring of the thickness of the endometrial layer and the growth of the follicle. At a certain stage, ovulation triggers are introduced and after a few days (from 3 to 5) the embryo is transferred to the uterus. This regimen is recommended for patients with a stable menstrual cycle and healthy ovulation.

The HRT protocol is performed for women with ovarian dysfunction. Its goal is to create an artificial hormonal cycle, which should lead to an increase in the required thickness of the endometrium. When it becomes more than 9 mm, the doctor prescribes drugs to prepare the uterus for implantation. Usually, the transfer occurs 5 days after you start taking these drugs.

Cryo-transfer in a stimulated cycle involves the activation of ovulation with small doses of gonadotropin hormones. The procedure is recommended for patients with insufficiently formed endometrial thickness in the natural cycle. When the follicles reach 18-20 mm, an injection of gonadotropin is prescribed and on the 4th-5th day the embryo is implanted into the uterine cavity.

As the specialists of the K + 31 clinic note, the effectiveness of cryotransfer does not depend on the chosen scheme. The technique is selected in accordance with the individual characteristics of the organism.

If you look at the reviews of our patients who underwent IVF according to the cryoprotocol, we can note a large number of positive ones among them. At the same time, special attention is paid to the respect for the female body and to the preservation of the possibility of getting pregnant by doctors in the future.

The cryoprotocol is a chance to experience the joy of motherhood.

A positive result from treatment can only be obtained by seeking professional help. Self-acting can be hazardous to health.


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