Average hemoglobin content in erythrocytes (MCH)


MCH is a unique erythrocyte index of a general blood test, the determination of which is of great importance for the differential diagnosis of various forms of anemia. Together with this indicator, MCHC, MCV, RDW and some others are determined. Shows the absolute mass of all hemoglobin molecules in one red blood cell. This characterizes the features of the functioning of the internal organs responsible for the synthesis of the protein-hemoglobin, as well as the normal formation and maturation of RBCs.

The norm is 27-31pg. Decrease (hypochromic state) is typical for:

  • Iron deficiency, which leads to insufficient synthesis of Hb and, accordingly, a reduced supply of it to erythrocytes;

  • Protein metabolism disorders;

  • Lead poisoning;

  • Thalassemias are a genetically determined pathology of the formation of globular proteins.

Hyperchromia or an increase in MCH occurs when:

  • Lack of folic acid and vitamin B12 - megaloblastic anemia;

  • Liver disease;

  • Bone marrow damage;

  • Long-term use of contraceptives and anticonvulsants;

  • Hypothyroidism.

For a reliable assessment of MCH, it is necessary to contact a specialist who, in combination with the results of other analyzes, will be able to make the correct diagnosis or prescribe clarifying studies if necessary.

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